Hormone allergy

American Journal of Reproductive Immunology : AJRI
Russell R RobyAristo Vojdani

Abstract

Estrogen and progesterone have been associated in women with symptoms that include asthma, migraine, dermatitis and pain. We suggest a connection between symptoms associated with hormone changes to a hormone antibody response. For IgG, IgM and IgE antibodies to progesterone, blood samples were obtained from 288 healthy control subjects by a commercial lab in California. Blood from 270 patients in Texas with changes in symptoms associated with menstrual cycles was examined. For IgE antibodies to both progesterone and estrogen, blood samples were obtained from an additional 32 healthy control subjects who had no symptoms related to menses and from 98 patients with symptoms associated with menstrual cycles. The symptoms were asthma, migraines and joint pain. At 2 S.D. above the mean values of control subjects, a significant number of patients show high levels of IgG, IgM and IgE antibodies to progesterone and estrogen. This paper describes evidence of antibodies to the hormones estrogen and progesterone. Progesterone, estrogen and their metabolites, after binding to human tissue proteins, such as albumin or globulin, may act as antigens and promote Type 2 helper cell development, thereby regulating antibody synthesis and allergy. ...Continue Reading

References

Jan 1, 1986·The Journal of Allergy and Clinical Immunology·O EliassonA C DeGraff
Mar 1, 1969·Tetrahedron Letters·R W Kelly
Nov 1, 1984·Thorax·C J GibbsR J White
Sep 1, 1982·The Journal of Clinical Endocrinology and Metabolism·K L CheesmanR M Radvany
Sep 30, 1995·Annals of the New York Academy of Sciences·J FishmanN T Telang
Sep 9, 1996·Archives of Internal Medicine·E M SkobeloffT V Alessi
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·E L CavalieriE G Rogan
Apr 3, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Catherine L HaggertyGrant W Waterer
May 31, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Joy L Snyder, Guha Krishnaswamy
Dec 1, 1963·Journal of Psychosomatic Research·L REES
Jul 28, 2004·Neurology·E Anne MacGregor, Allan Hackshaw
Feb 1, 1947·The Journal of Obstetrics and Gynaecology of the British Empire·B ZONDEK, Y M BROMBERG

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Citations

Mar 23, 2011·Journal of Women's Health·I Leonard BernsteinJonathan A Bernstein
Jun 1, 2008·Expert Opinion on Medical Diagnostics·Aristo Vojdani
May 31, 2011·Otolaryngologic Clinics of North America·Charles S Ebert, Harold C Pillsbury
Aug 31, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Antonio Pereira-VegaFrancisco L Gil
Apr 9, 2008·Allergy·E Jensen-Jarolim, E Untersmayr
Jan 16, 2007·American Journal of Reproductive Immunology : AJRI·Alek M ItseksonHoward J A Carp
Jul 3, 2013·Journal of Reproductive Immunology·Mohamed I EllaithyMarwa S Taha
Dec 10, 2016·Expert Review of Respiratory Medicine·José L Sánchez-RamosFrancisco Gómez-Real
Jan 9, 2018·The World Allergy Organization Journal·E UntersmayrK Walch

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