Hormone-sensitive adenylate cyclase in human colonic mucosa

Digestion
B SimonH Kather

Abstract

Human colonic adenylate cyclase has been shown to be sensitive to vasoactive intestinal polypeptide (VIP) and prostaglandins of the E- and F-type. Maximal activation of enzyme activity averaged 200% for VIP and 300-350% for the E-prostaglandins. Both classes of hormones had an additive effect on enzyme activity indicating the existence of two distinct hormone-sensitive adenylate cyclases in human colonic mucosa.

Citations

Dec 1, 1980·Digestive Diseases and Sciences·L C Racusen, H J Binder
Feb 1, 1980·Digestive Diseases and Sciences·B Simon, H Kather
Jan 14, 1980·Life Sciences·J HardcastleJ S Redfern
Jan 1, 1983·Pharmacology, Biochemistry, and Behavior·H K SeitzB Kommerell
Jan 1, 1989·Comparative Biochemistry and Physiology. A, Comparative Physiology·M B Hansen, N Bindslev
Apr 1, 1984·Gut·A A AnagnostidesS R Bloom
Jan 1, 1985·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·H K SeitzS Veith
Jun 1, 1980·European Journal of Clinical Investigation·B Simon, H Kather
Oct 1, 1978·European Journal of Clinical Investigation·B SimonH Kather

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