Hormone therapy in men and risk of cardiac allograft rejection

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Richard S SchofieldJuan M Aranda

Abstract

Hormone therapy with leuprolide acetate (Lupron) is frequently used to treat prostate cancer, a common malignancy expected to be diagnosed in >180,000 men in the United States this year. In addition, testosterone supplementation is frequently recommended for adult men with reduced libido or impotence and decreased serum levels of testosterone. Although these hormone therapies are generally considered benign, we describe 3 cases of acute cardiac rejection temporally associated with the use of these drugs in men who have undergone cardiac transplantation. To our knowledge, this is the first such description of this phenomenon in the literature.

References

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Citations

Aug 17, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Siamak MohammadiIradj Gandjbakhch
Jul 23, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·R TandlerM Weyand
Mar 25, 2008·Transplantation·Jessica FleischerElizabeth Shane
Apr 20, 2011·American Journal of Reproductive Immunology : AJRI·Jay F KirkpatrickKimberly M Frank
Feb 4, 2009·Journal of Neuroendocrinology·D C SkinnerN Scanlan-Blake

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