Abstract
There is a growing population of women who have or will undergo hematopoietic stem cell transplant for a variety of malignant and benign conditions. Gynecologists play an important role in addressing the gynecologic and reproductive health concerns for these women throughout the transplant process. As women undergo cell transplantation, they should avoid becoming pregnant and are at risk of uterine bleeding. Thus, counseling about and implementing hormonal treatments such as gonadotropin-releasing hormone agonists, combined hormonal contraceptives, and progestin-only methods help to achieve therapeutic amenorrhea and can serve as contraception during the peritransplant period. In this commentary, we summarize the timing, risks, and benefits of the hormonal options just before, during, and for the year after hematopoietic stem cell transplantation.
References
Sep 1, 2006·Cancer·Dror MeirowDina Ben-Yehuda
Oct 3, 2006·Obstetrics and Gynecology·Malcolm G MunroLorena Barreda
May 1, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Alexander M Quaas, Elizabeth S Ginsburg
Oct 2, 2007·Obstetrics and Gynecology·Eric D LevensAlan H DeCherney
Oct 24, 2007·Bone Marrow Transplantation·J LiuE Carrier
Nov 6, 2007·Clinical Obstetrics and Gynecology·Jessica Kiley, Cassing Hammond
May 16, 2008·Blood·David E GerberMichael B Streiff
May 22, 2008·Obstetrical & Gynecological Survey·Meredith K Martin-JohnstonAlicia Armstrong
Jul 17, 2008·Journal of Thrombosis and Haemostasis : JTH·A GonsalvesD S Allan
Nov 5, 2010·Clinical Obstetrics and Gynecology·S Samuel KimBrian Petroff
Dec 25, 2010·Obstetrical & Gynecological Survey·Colleen L Milroy, Kirtly Parker Jones
Jul 21, 2011·JAMA : the Journal of the American Medical Association·Lucia Del MastroMarco Venturini
Jan 10, 2012·Seminars in Hematology·Dana ShanisPamela Stratton
Mar 30, 2012·Reproductive Sciences·Kristof ChwaliszFrank Z Stanczyk
Sep 1, 2012·Fertility and Sterility·Zeev BlumenfeldTsila Zuckerman
Jun 13, 2013·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Sukhbir SinghUNKNOWN CLINICAL PRACTICE – GYNAECOLOGY COMMITTEE
Aug 3, 2013·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailKaren M Kuntz
Sep 10, 2013·Fertility and Sterility·UNKNOWN Practice Committee of American Society for Reproductive Medicine
Jan 15, 2014·Bone Marrow Transplantation·S JoshiN S Majhail
Jul 23, 2014·Obstetrics and Gynecology
Mar 5, 2015·The New England Journal of Medicine·Halle C F MooreUNKNOWN POEMS/S0230 Investigators
Citations
Aug 24, 2019·Pediatric Blood & Cancer·Allison G CloseErika Friehling
Dec 19, 2020·Journal of Pediatric and Adolescent Gynecology·Katherine E Debiec, Nicole Todd
Jan 6, 2021·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists’ Committee on Adolescent Health Care