Hormone Use for Therapeutic Amenorrhea and Contraception During Hematopoietic Cell Transplantation

Obstetrics and Gynecology
Katherine ChangP Stratton

Abstract

There is a growing population of women who have or will undergo hematopoietic stem cell transplant for a variety of malignant and benign conditions. Gynecologists play an important role in addressing the gynecologic and reproductive health concerns for these women throughout the transplant process. As women undergo cell transplantation, they should avoid becoming pregnant and are at risk of uterine bleeding. Thus, counseling about and implementing hormonal treatments such as gonadotropin-releasing hormone agonists, combined hormonal contraceptives, and progestin-only methods help to achieve therapeutic amenorrhea and can serve as contraception during the peritransplant period. In this commentary, we summarize the timing, risks, and benefits of the hormonal options just before, during, and for the year after hematopoietic stem cell transplantation.

References

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Citations

Dec 19, 2020·Journal of Pediatric and Adolescent Gynecology·Katherine E Debiec, Nicole Todd
Jan 6, 2021·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists’ Committee on Adolescent Health Care

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