Hormones and tendinopathies: the current evidence

British Medical Bulletin
Francesco OlivaNicola Maffulli

Abstract

Tendinopathies negatively affect the quality of life of millions of people, but we still do not know the factors involved in the development of tendon conditions. Published articles in English in PubMed and Google Scholar up to June 2015 about hormonal influence on tendinopathies onset. One hundred and two papers were included following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. In vitro and in vivo, tenocytes showed changes in their morphology and in their functional properties according to hormonal imbalances. Genetic pattern, sex, age and comorbidities can influence the hormonal effect on tendons. The increasing prevalence of metabolic disorders prompts to investigate the possible connection between metabolic problems and musculoskeletal diseases. The influence of hormones on tendon structure and metabolism needs to be further investigated. If found to be significant, multidisciplinary preventive and therapeutic strategies should then be developed.

References

Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R I Schwarz, M J Bissell
Jan 1, 1991·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·J AyalaA Blanco
Jul 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S O AbrahamssonL S Lohmander
Feb 19, 1986·Biochimica Et Biophysica Acta·M K LeungL M Golub
Apr 20, 1993·Journal of Molecular Biology·T J WessJ D Baird
May 31, 1996·The Journal of Biological Chemistry·A ElgawishV M Monnier
Feb 1, 1997·Cell Biology and Toxicology·K Bernard-BeauboisM Adolphe
Jul 1, 1997·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·W P GrantA I Vinik
Sep 28, 1998·Biochimica Et Biophysica Acta·G B SajithlalG Chandrakasan
Oct 28, 1999·Clinical Chemistry and Laboratory Medicine : CCLM·Z TurkB Benko
Aug 29, 2000·International Journal of Sports Medicine·M PärssinenT Seppälä
Dec 12, 2001·Medicine and Science in Sports and Exercise·C TallonS W Ewen
Mar 13, 2002·Archives of Biochemistry and Biophysics·G Kesava ReddyChukuka S Enwemeka
Apr 23, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Timothy M Ritty, Jeremy Herzog
Jun 12, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G Kesava Reddy
Oct 18, 2003·Journal of Shoulder and Elbow Surgery·Andrew L ChenFrances Cuomo
Jan 13, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Nadia Chbinou, Jérôme Frenette
Jul 28, 2004·The Journal of Bone and Joint Surgery. British Volume·P HarvieA J Carr
Dec 2, 2004·Sports Medicine·Constantinos N MaganarisNicola Maffulli
Feb 11, 2005·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Valerie E ChoyDaniel A Martinez
May 20, 2005·Journal of the American Podiatric Medical Association·William P GrantRenee M Kukla
Jun 29, 2005·The American Journal of Sports Medicine·Gaonyadiwe G MokoneMalcolm Collins
Jan 21, 2006·The American Journal of Sports Medicine·Timothy E HewettKevin R Ford
Jan 25, 2006·Scandinavian Journal of Medicine & Science in Sports·G G MokoneM Collins
Feb 24, 2006·The Biochemical Journal·Jennifer R MackleySteven J Winder
Jul 25, 2006·The American Journal of Sports Medicine·Fred A WentorfCathy S Carlson
Dec 6, 2006·Foot & Ankle International·George B Holmes, Johnny Lin
Dec 26, 2006·Journal of Shoulder and Elbow Surgery·Paul HarvieAndrew J Carr
Feb 24, 2007·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·M AkturkM Arslan
Aug 19, 2007·International Journal of Experimental Pathology·S Peter MagnussonMichael Kjaer
Sep 18, 2007·Journal of Science and Medicine in Sport·Merzesh Magra, Nicola Maffulli
May 31, 2008·Foot & Ankle International·Fábio BatistaRamon S Campos

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Citations

Sep 8, 2016·Journal of Diabetes and Its Complications·Shih-Wei HuangHui-Wen Lin
Nov 12, 2016·BMC Musculoskeletal Disorders·Christoph SpangLudvig J Backman
Jan 5, 2018·Expert Opinion on Biological Therapy·Isabel AndiaNicola Maffulli
May 19, 2018·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Etienne J O O'Brien, Roger K W Smith
Sep 1, 2018·Journal of Biomechanical Engineering·K A BonillaL J Soslowsky
Dec 3, 2016·BMJ Open Sport & Exercise Medicine·Md Abdul AlimPaul W Ackermann
Apr 5, 2019·The Journal of Bone and Joint Surgery. American Volume·Stefano GuminaVittorio Candela
May 19, 2019·Scandinavian Journal of Medicine & Science in Sports·Francesco AddevicoPaul W Ackermann
Jul 14, 2017·The Journal of Orthopaedic and Sports Physical Therapy·Kesava Kovanur SampathSteve Tumilty
Jan 15, 2020·Connective Tissue Research·Stefania L WunderliJess G Snedeker
Feb 8, 2020·BMC Musculoskeletal Disorders·George JomaaChrister Rolf
Mar 13, 2020·The Journal of Sports Medicine and Physical Fitness·Mariusz NaczkAlicja Naczk
Jun 9, 2020·Expert Opinion on Pharmacotherapy·Rocco AicaleNicola Maffulli
Aug 17, 2018·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Michael L CeravoloRichard J Keegan
Apr 4, 2017·British Medical Bulletin·Leonardo OstiNicola Maffulli
Jun 12, 2019·Case Reports in Orthopedics·Andrew M SchwartzKyle Hammond
Apr 18, 2020·Scientific Reports·Yasser Alakhdar MohmaraSergio Hernandez-Sanchez
Mar 20, 2020·BMJ Case Reports·Sriskandarasa Senthilkumaran, William M Ledingham
Jul 29, 2019·BMC Musculoskeletal Disorders·Tianpeng XuDechun Geng
Oct 1, 2020·Journal of Foot and Ankle Research·Rocco AicaleNicola Maffulli
Feb 4, 2021·Porto Biomedical Journal·Sofia Dimitri-PinheiroApostolos Karantanas
Aug 12, 2021·Journal of Manipulative and Physiological Therapeutics·Kesava Kovanur SampathSteve Tumilty
Sep 26, 2020·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Alessio Giai ViaNicola Maffulli

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