Hospital acquired vancomycin resistant enterococci in surgical intensive care patients - a prospective longitudinal study

Antimicrobial Resistance and Infection Control
Stefanie KampmeierAlexander Mellmann

Abstract

Vancomycin resistant enterococci (VRE) occur with enhanced frequency in hospitalised patients. This study elucidates the prevalence of VRE on admission among surgical intensive care unit (SICU) patients, whether these patients are at special risk for VRE acquisition and which risk factors support this process. Patients admitted to SICUs of the University Hospital Münster were examined during August-October 2017. VRE screening was performed within 48 h after admission and directly prior to discharge of patients. In parallel risk factors were recorded to estimate their effect on VRE acquisition during SICU stay. In total, 374 patients (68% male) with a median age of 66 years were admitted to one of the SICUs during the investigation period. Of all, 336 patients (89.8%) were screened on admission and 268 (71.7%) on discharge. Nine patients were admitted with previously known VRE colonisation. Twelve (3.6%) further patients were VRE positive on admission. During ICU stay, eight (3.0%) additional patients turned out to be VRE colonised. Risk factors found to be significantly associated with VRE acquisition were median length of stay on the ICU (14 vs. 3 days; p = 0.01), long-term dialysis (12.5% vs. 2.0% of patients; p = 0.05), and ...Continue Reading

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Citations

Sep 29, 2019·Microorganisms·Carlos L Correa-MartinezStefanie Kampmeier
Jul 24, 2020·The Journal of Antimicrobial Chemotherapy·Kyriaki XanthopoulouUNKNOWN DZIF R-Net Study Group
Dec 13, 2019·Antimicrobial Resistance and Infection Control·Pao-Yu ChenShan-Chwen Chang
Oct 8, 2020·Journal of Clinical Laboratory Analysis·Fatma ErdemZerrin Aktas
Jan 15, 2021·International Journal of Environmental Research and Public Health·Anna Gotkowska-Płachta
Jul 23, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Akram N SalahMahmoud A Yassien
Sep 11, 2020·American Journal of Therapeutics·Waqas AslamShekhar Ghamande
Mar 6, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Fardad EjtehadiSeyed Ali Malekhosseini
Apr 4, 2020·Infectious Disorders Drug Targets·Nanditha Rajaram BhatBiranthabail Dhanashree

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Methods Mentioned

BETA
PCR

Software Mentioned

SeqSphere +
cgMLST

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