Hospital networks and the dispersal of hospital-acquired pathogens by patient transfer.

PloS One
Tjibbe DonkerHajo Grundmann

Abstract

Hospital-acquired infections (HAI) are often seen as preventable incidents that result from unsafe practices or poor hospital hygiene. This however ignores the fact that transmissibility is not only a property of the causative organisms but also of the hosts who can translocate bacteria when moving between hospitals. In an epidemiological sense, hospitals become connected through the patients they share. We here postulate that the degree of hospital connectedness crucially influences the rates of infections caused by hospital-acquired bacteria. To test this hypothesis, we mapped the movement of patients based on the UK-NHS Hospital Episode Statistics and observed that the proportion of patients admitted to a hospital after a recent episode in another hospital correlates with the hospital-specific incidence rate of MRSA bacteraemia as recorded by mandatory reporting. We observed a positive correlation between hospital connectedness and MRSA bacteraemia incidence rate that is significant for all financial years since 2001 except for 2008-09. All years combined, this correlation is positive and significantly different from zero (partial correlation coefficient r = 0.33 (0.28 to 0.38)). When comparing the referral pattern for Engli...Continue Reading

References

Mar 31, 1998·Journal of Epidemiology and Community Health·V S Raleigh, V A Kiri
Aug 10, 2000·Nature·R AlbertA L Barabasi
Mar 22, 2001·Nature·S H Strogatz
Feb 15, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M EveillardF Fauvelle
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Mark C EnrightBrian G Spratt
Jun 13, 2002·Proceedings of the National Academy of Sciences of the United States of America·M Girvan, M E J Newman
Aug 31, 2002·Science·E RavaszA L Barabási
May 21, 2004·Nature Reviews. Microbiology·Fernando Baquero
Jun 29, 2004·Proceedings of the National Academy of Sciences of the United States of America·B S CooperS Ebrahim
Jan 15, 2005·Journal of Epidemiology and Community Health·Laura M WoodsMichel P Coleman
Oct 4, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Aaron Clauset
Jun 19, 2009·Medical Care·Theodore J IwashynaDavid A Asch
Oct 22, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Faranak AnsariPeter Davey
Jan 20, 2010·PLoS Medicine·Hajo GrundmannUNKNOWN European Staphylococcal Reference Laboratory Working Group
Apr 14, 2010·PLoS Computational Biology·Marcel Salathé, James H Jones
Sep 30, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Susan S HuangBruce Y Lee
Nov 3, 2011·PloS One·Tavis K Anderson, Michael V K Sukhdeo
Dec 14, 2011·PloS One·Dapeng Hao, Chuanxing Li
Sep 26, 2012·Enfermedades infecciosas y microbiología clínica·Núria FreixasUNKNOWN VINCat Program

❮ Previous
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Citations

Jan 29, 2014·Proceedings of the National Academy of Sciences of the United States of America·Mariano CiccoliniMark E J Woolhouse
Oct 2, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·A JurkeAw Friedrich
May 24, 2016·Nature Microbiology·Kathy E RavenSharon J Peacock
Nov 26, 2015·Lancet·Alison H HolmesLaura J V Piddock
Jul 25, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Manon R HaverkateMary K Hayden
Apr 8, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Carline van den DoolJacco Wallinga
Jun 16, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jacob E SimmeringPhilip M Polgreen
Mar 19, 2013·International Journal of Medical Microbiology : IJMM·Mariano CiccoliniAlexander W Friedrich
Jul 26, 2015·The Lancet. Respiratory Medicine·Timothy J KiddUNKNOWN ACPinCF Investigator Group
Mar 31, 2015·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M LindqvistA Hällgren
Jun 16, 2016·Frontiers in Microbiology·Daniela M GeraciUNKNOWN NICU Surveillance Study Group
Aug 4, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael J RayWilliam E Trick
Jan 18, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Claire L GorrieKathryn E Holt
Feb 8, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael J RayWilliam E Trick
Nov 5, 2016·Australian Health Review : a Publication of the Australian Hospital Association·Hassan AssarehStephen R Leeder
Aug 25, 2017·PLoS Computational Biology·Narimane NekkabPascal Crépey
May 25, 2018·Research and Theory for Nursing Practice·Sharon Lea Kurtz
Oct 13, 2017·Journal of the American Medical Informatics Association : JAMIA·Jason Cory Brunson, Reinhard C Laubenbacher
Aug 24, 2019·Nature Microbiology·Sara Hernando-AmadoJosé L Martínez
Oct 28, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kristen BushMartin S Zand
Oct 22, 2019·Current Opinion in Gastroenterology·Jasper P VinkJonathan D Edgeworth
Jul 18, 2018·Translational Behavioral Medicine·Eva H DuGoffCraig Evan Pollack
Apr 13, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel K SewellPhilip M Polgreen
Apr 25, 2019·Medicine, Health Care, and Philosophy·Alistair Wardrope
Oct 22, 2019·Statistics in Medicine·Daniel K Sewell, UNKNOWN CDC MInD-Healthcare Program
May 23, 2016·BMC Infectious Diseases·Cheryl L GibbonsMargo E Chase-Topping
Aug 2, 2019·Antimicrobial Resistance and Infection Control·J KeizerJ E W C Van Gemert-Pijnen
Feb 20, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Lara Tavoschi On Behalf Of The Tuscan Clinical Microbiology Laboratory Network
Dec 1, 2020·PLoS Computational Biology·Monika J PiotrowskaRafael T Mikolajczyk
Aug 31, 2016·Nature Microbiology·Kathy E RavenSharon J Peacock

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