Hospital volume of esophageal cancer surgery in relation to outcomes from primary anti-reflux surgery.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
Sheraz R MarkarJesper Lagergren

Abstract

No previous study has sought to identify the effect of hospital volume of esophagectomy on anti-reflux surgery outcomes. The hypothesis under investigation was hospitals performing esophagectomies, particularly those of higher annual volume, have better outcomes from primary anti-reflux surgery. This population-based cohort study included adult individuals (≥18 years) in Sweden receiving primary anti-reflux surgery for a recorded gastro-esophageal reflux disease in 1997-2010, with follow-up until 2013 The 'exposure' was hospital volume of esophagectomy, with hospitals conducting esophagectomies divided into 0, >0-1, >1-3 and ≥ 4 based on annual volume, and hospitals not conducting esophagectomies were the reference category. The outcomes were 30-day re-intervention and surgical re-intervention during the entire follow-up after anti-reflux surgery. Multivariable Cox regression provided hazard ratios (HRs) with 95% confidence intervals (CIs), adjusted for age, sex, comorbidity, type of anti-reflux surgery, and year of anti-reflux surgery. Among 10,959 participants having undergone primary anti-reflux surgery, the 30-day re-intervention rate was 1.1%, and the rate of surgical re-intervention during the entire follow-up was 6.8%. C...Continue Reading

References

Apr 12, 2002·The New England Journal of Medicine·John D BirkmeyerDavid E Wennberg
Dec 12, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Bas P L WijnhovenDavid I Watson
Nov 17, 2009·BMC Health Services Research·Thomas R PalserJan Hp van der Meulen
Mar 23, 2010·The British Journal of Surgery·J N ArmitageUNKNOWN Royal College of Surgeons Co-morbidity Consensus Group
Jun 3, 2011·The New England Journal of Medicine·Jonathan F FinksJohn D Birkmeyer
Nov 18, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sheraz R MarkarDonald E Low
Jan 9, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Maryam DerogarJesper Lagergren
Feb 8, 2014·Gastroenterology Clinics of North America·Joel H Rubenstein, Joan W Chen
Mar 10, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sheraz R MarkarJesper Lagergren
Sep 13, 2017·JAMA : the Journal of the American Medical Association·John Maret-OudaJesper Lagergren
Dec 1, 2018·Annals of Surgery·Sheraz R MarkarGeorge B Hanna
Jul 6, 2019·Annals of Surgery·Nathan J CurtisNader K Francis
Oct 17, 2019·The New England Journal of Medicine·Stuart J SpechlerGrant D Huang

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