Abstract
Details of patients hospitalized for asthma exacerbation in mainland China are lacking. To improve disease control and reduce economic burden, a large sample survey among this patient population is indispensable. This study aimed to investigate the clinical characteristics and outcomes of such patients. A retrospective study was conducted on patients hospitalized for asthma exacerbation in 29 hospitals of 29 regions in mainland China during the period 2013 to 2014. Demographic features, pre-admission conditions, exacerbation details, and outcomes were summarized. Risk factors for exacerbation severity were analyzed. There were 3,240 asthmatic patients included in this study (57.7% females, 42.3% males). Only 28.0% used daily controller medications; 1,287 (39.7%) patients were not currently on inhaled corticosteroids. Acute upper airway infection was the most common trigger of exacerbation (42.3%). Patients with severe to life-threatening exacerbation tended to have a longer disease course, a smoking history, and had comorbidities such as hypertension, chronic obstructive pulmonary disease (COPD), and food allergy. The multivariate analysis showed that smoking history, comorbidities of hypertension, COPD, and food allergy were i...Continue Reading
References
May 2, 1990·JAMA : the Journal of the American Medical Association·K B Weiss
Oct 22, 1998·The New England Journal of Medicine·P LangeG Jensen
Apr 15, 2004·Allergy·Matthew MasoliUNKNOWN Global Initiative for Asthma (GINA) Program
Jun 17, 2006·American Journal of Respiratory and Critical Care Medicine·Vidya KrishnanJerry A Krishnan
Jan 6, 2007·American Journal of Respiratory and Critical Care Medicine·Stephen C LazarusUNKNOWN National Heart Lung and Blood Institute's Asthma Clinical Research Network
Apr 28, 2007·Respiratory Medicine·Louise WatsonStephen T Holgate
Jul 31, 2007·The Journal of Allergy and Clinical Immunology·Malcolm R Sears, Neil W Johnston
Sep 25, 2007·Chest·Vincenzo BelliaRaffaele Antonelli Incalzi
Oct 17, 2007·Annals of Internal Medicine·Erik von ElmUNKNOWN STROBE Initiative
Dec 13, 2007·Proceedings of the American Thoracic Society·Neil W Johnston
Dec 25, 2007·Gender Medicine·Dirkje S Postma
Aug 22, 2008·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Louis-Philippe BouletKenneth R Chapman
Feb 25, 2009·Thorax·C K W LaiUNKNOWN International Study of Asthma and Allergies in Childhood Phase Three Study Group
Jan 17, 2013·The Journal of Allergy and Clinical Immunology·Matthew A RankColin P West
Aug 29, 2014·Annals of the American Thoracic Society·Teresa ToAndrea Gershon
May 23, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Yasuhiro YamauchiTakahide Nagase
Nov 26, 2015·International Archives of Allergy and Immunology·Bani Preet KaurDiane Levine
Sep 16, 2017·Allergy, Asthma & Immunology Research·Seung Won LeeMan Yong Han