Hospitalization, frequency of interventions, and quality of life after endoscopic, surgical, or conservative treatment in patients with chronic pancreatitis.

World Journal of Surgery
Karoline RutterM Schindl

Abstract

Patients with chronic pancreatitis usually have a long and debilitating history of disease with frequent hospital admissions, episodes of intractable pain and multiple interventions. The sequences of treatment at initial presentation, endoscopy, surgery, or conservative treatment may affect the time course and admissions needed for disease control, thereby determining quality of life and overall outcome. A total of 292 patients with initial endoscopic, surgical, or conservative pharmacological treatment were retrospectively analyzed regarding frequency of interventions, days in hospital, symptom-free intervals, morbidity, and mortality. Quality of life (QoL) at the latest follow-up was measured by two standardized quality of life questionnaires (EORTC C30 and PAN26). Endoscopic treatment was initially performed in 150 (51.4%) patients, whereas 99 (33.9%) underwent surgery and 43 (14.7%) patients were treated conservatively at their initial presentation. Patients who underwent surgery had a significantly shorter time in the hospital (25.3 ± 24.6, 34.4 ± 35.1, 61.1 ± 37.9; P < 0.001), fewer subsequent therapies (0.43 ± 1.0, 2.1 ± 2.4, 3.1 ± 3.0; P ≤ 0.001), and a longer relapse-free interval (P = 0.004) compared with endoscopical...Continue Reading

References

May 20, 1993·The New England Journal of Medicine·A B LowenfelsL Domellöf
Oct 26, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D FitzsimmonsT Tihanyi
Feb 17, 2001·Gastroenterology·B Etemad, D C Whitcomb
Dec 26, 2001·Zentralblatt für Chirurgie·H WitzigmannJ Hauss
Mar 1, 2002·American Journal of Surgery·Wolfgang SchlosserHans G Beger
Sep 24, 2002·Endoscopy·T RöschUNKNOWN European Society of Gastrointestinal Endoscopy Research Group
Jun 19, 2004·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J MayerleC-D Heidecke
Jun 28, 2005·Gastroentérologie Clinique Et Biologique·Eric BartoliJean-Louis Dupas
Feb 16, 2007·The New England Journal of Medicine·Djuna L CahenMarco J Bruno
Jun 18, 2008·Endoscopy·N EleftherladisJ Devière
Dec 17, 2009·Annals of Surgery·Dana K Andersen, Charles F Frey

❮ Previous
Next ❯

Citations

Jun 20, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Catherine J YangJennifer F Tseng
Apr 18, 2015·Pancreas·Catherine J YangJennifer F Tseng
Jul 28, 2015·World Journal of Emergency Surgery : WJES·Federico CoccoliniLuca Ansaloni
Feb 26, 2016·Scandinavian Journal of Gastroenterology·Taija KorpelaLeena Kylänpää
Oct 28, 2016·Gut and Liver·Manu TandanDuvvur Nageshwar Reddy
Apr 29, 2018·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Rushikesh ShahEmad Qayed

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.