Hospitalizations for opioid poisoning: a nation-wide population-based study in Denmark, 1998-2004

Addiction
Anne-Mette Bay BjørnSteffen Christensen

Abstract

To assess hospitalization rates (HR) for poisoning with heroin, methadone or strong analgesics and relate them to quantities of prescribed methadone and strong analgesics in Denmark between 1998 and 2004. Population-based ecological study. We extracted data on all emergency department visits and hospital admissions registered in the Danish National Patient Registry with a diagnosis of poisoning with heroin (n = 1688), methadone (n = 173) or strong analgesics (n = 384). To ascertain sale of prescribed medications we used data from the Danish Medicines Agency. Age- and gender-standardized HR and defined daily doses (DDD) per 1000 people per day. HR for heroin poisoning was 4.4 [95% confidence interval (CI): 3.8-4.9] per 100,000 person-years (p-y) in 1998 and 4.6 (CI: 4.0-5.2) per 100,000 p-y in 2004. HR for methadone poisoning increased from 0.1 (CI: 0.0-0.2) per 100,000 p-y in 1998 to 1.1 (CI: 0.8-1.4) per 100,000 p-y in 2004. HR for poisoning with strong analgesics increased from 0.6 (CI: 0.4-0.9) per 100,000 p-y in 1998 to 2.1 (CI: 1.8-2.6) per 100,000 p-y in 2004. The sale of prescribed strong analgesics (5.0 DDD per 1000 people per day in 1998 to 5.9 DDD in 2004) and methadone (3.0 DDD per 1000 people per day in 1998 to 3.4 ...Continue Reading

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Citations

Sep 26, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Corinde E WiersFelix Bermpohl
Apr 23, 2010·American Journal of Preventive Medicine·Jeffrey H CobenRobert M Bossarte
Feb 3, 2015·Journal of Substance Abuse Treatment·Ifeoma N OnyekaJussi Kauhanen

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