Abstract
To assess hospitalization rates (HR) for poisoning with heroin, methadone or strong analgesics and relate them to quantities of prescribed methadone and strong analgesics in Denmark between 1998 and 2004. Population-based ecological study. We extracted data on all emergency department visits and hospital admissions registered in the Danish National Patient Registry with a diagnosis of poisoning with heroin (n = 1688), methadone (n = 173) or strong analgesics (n = 384). To ascertain sale of prescribed medications we used data from the Danish Medicines Agency. Age- and gender-standardized HR and defined daily doses (DDD) per 1000 people per day. HR for heroin poisoning was 4.4 [95% confidence interval (CI): 3.8-4.9] per 100,000 person-years (p-y) in 1998 and 4.6 (CI: 4.0-5.2) per 100,000 p-y in 2004. HR for methadone poisoning increased from 0.1 (CI: 0.0-0.2) per 100,000 p-y in 1998 to 1.1 (CI: 0.8-1.4) per 100,000 p-y in 2004. HR for poisoning with strong analgesics increased from 0.6 (CI: 0.4-0.9) per 100,000 p-y in 1998 to 2.1 (CI: 1.8-2.6) per 100,000 p-y in 2004. The sale of prescribed strong analgesics (5.0 DDD per 1000 people per day in 1998 to 5.9 DDD in 2004) and methadone (3.0 DDD per 1000 people per day in 1998 to 3.4 ...Continue Reading
References
Jan 1, 1995·Annual Review of Public Health·H Morgenstern
Jan 1, 1997·Acta Anaesthesiologica Scandinavica·T G Clausen
Mar 2, 1999·Acta Oncologica·A Vainio
Dec 21, 2002·Addiction·Carolyn DayKate Dolan
Feb 22, 2003·BMJ : British Medical Journal·Karl A Sporer
Feb 27, 2004·The Medical Journal of Australia·Raymond F MartyresJane M Burns
Jun 16, 2005·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Jürgen RehmLudwig Kraus
Jul 19, 2005·Drug and Alcohol Dependence·Wilson M Compton, Nora D Volkow
Aug 30, 2005·Annals of Emergency Medicine·UNKNOWN National Institute of Neurological Disorders Stroke rt-PA Stroke Study Group
Nov 18, 2005·Forensic Science International : Synergy·A SteentoftD Rollmann
Nov 22, 2005·Drug and Alcohol Review·Shane DarkeMaree Teesson
Dec 31, 2005·Neonatal Network : NN
May 4, 2006·Addiction·Evan WoodThomas Kerr
Jul 18, 2006·Appetite·Annemette Nielsen
Jul 25, 2006·Pharmacoepidemiology and Drug Safety·Leonard J PaulozziYongli Xi
Jul 26, 2006·The American Journal of Drug and Alcohol Abuse·David W BrookChenshu Zhang
Nov 2, 2006·International Journal of Epidemiology·Oliver MorganMatthew Hickman
Nov 23, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Benedikt FischerMichelle Firestone Cruz
Apr 25, 2007·The Clinical Neuropsychologist·UNKNOWN American Academy of Clinical Neuropsychology
Sep 22, 2007·Drug and Alcohol Dependence·Amanda Roxburgh, Louisa Degenhardt
Oct 23, 2008·Journal of the American College of Cardiology·Anthony N DeMaria
Citations
Sep 26, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Corinde E WiersFelix Bermpohl
Apr 23, 2010·American Journal of Preventive Medicine·Jeffrey H CobenRobert M Bossarte
Feb 3, 2015·Journal of Substance Abuse Treatment·Ifeoma N OnyekaJussi Kauhanen
Nov 1, 2020·BMJ Open·Yves GallienMarie Michèle Thiam