Host Factors Independently Associated With Prognosis in Patients With Oral Cavity Cancer.

JAMA Otolaryngology-- Head & Neck Surgery
Cristina ValeroSnehal G Patel

Abstract

The association and interaction of host characteristics with prognosis in patients with oral cavity squamous cell carcinoma (OSCC) are poorly understood. There is increasing evidence that host characteristics are associated with treatment outcomes of many cancers. To examine the host factors associated with prognosis in patients with OSCC and their interactions to create a numerical index that quantifies the prognostic capacity of these host characteristics. This retrospective cohort study included patients with OSCC treated surgically at a tertiary care center from January 1, 1998, to December 31, 2015. From a departmental OSCC database of 1377 previously untreated patients, 68 patients with missing data on any host variable of interest within a month before the start of treatment were excluded, leaving 1309 patients. Data analysis was performed from October 21, 2019, to December 10, 2019. Primary surgery for OSCC. Overall survival (OS) was the primary end point, and disease-specific survival (DSS) was the secondary end point. Optimal cutoffs for each variable were identified using recursive-partitioning analysis with the classification and regression tree method using OS as the dependent variable. Body mass index (BMI) and pr...Continue Reading

References

Oct 9, 2002·Archives of Otolaryngology--head & Neck Surgery·Jay F PiccirilloEdward L Spitznagel
Sep 27, 2003·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Ulrich SchäferNormann Willich
Aug 16, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Marianne NordsmarkJens Overgaard
Feb 1, 2006·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Peter VaupelMichael Höckel
May 22, 2008·Journal of Surgical Oncology·Snehal G Patel, William M Lydiatt
Sep 26, 2012·Journal of Cancer Research and Clinical Oncology·Franziska PeterOrlando Guntinas-Lichius
May 31, 2014·Journal of the National Cancer Institute·Arnoud J TempletonEitan Amir
Jun 18, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Yasemin Benderli CihanHasan Mutlu
Mar 2, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Martin GrimmSiegmar Reinert
Sep 4, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Manupol TangthongkumWattana Sinkitjaroenchai
Mar 14, 2018·Asia-Pacific Journal of Clinical Oncology·Yisheng WeiChuyuan Hong
May 4, 2018·Radiation Oncology·Pierfrancesco FrancoAndrea Casadei Gardini
Aug 22, 2018·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Yuan ChenWendong Gu
Nov 25, 2018·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·K Holub, A Biete
Apr 7, 2019·Anticancer Research·Dante DE PazShiang-Fu Huang
Jul 25, 2019·Oncology Research and Treatment·Abdullah SakinSener Cihan

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Citations

Jan 31, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Piergiorgio GaudiosoPaolo Boscolo-Rizzo
Jun 20, 2021·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Anjali PillaiSnehal G Patel
Aug 18, 2021·Laryngoscope Investigative Otolaryngology·Paolo Boscolo-RizzoGiancarlo Tirelli
Sep 4, 2021·International Journal of General Medicine·Yanling WenXiaoyan Han

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