Host factors involved in influenza virus infection

Emerging Topics in Life Sciences
Matloob Husain

Abstract

Influenza virus causes an acute febrile respiratory disease in humans that is commonly known as 'flu'. Influenza virus has been around for centuries and is one of the most successful, and consequently most studied human viruses. This has generated tremendous amount of data and information, thus it is pertinent to summarise these for, particularly interdisciplinary readers. Viruses are acellular organisms and exist at the interface of living and non-living. Due to this unique characteristic, viruses require another organism, i.e. host to survive. Viruses multiply inside the host cell and are obligate intracellular pathogens, because their relationship with the host is almost always harmful to host. In mammalian cells, the life cycle of a virus, including influenza is divided into five main steps: attachment, entry, synthesis, assembly and release. To complete these steps, some viruses, e.g. influenza utilise all three parts - plasma membrane, cytoplasm and nucleus, of the cell; whereas others, e.g. SARS-CoV-2 utilise only plasma membrane and cytoplasm. Hence, viruses interact with numerous host factors to complete their life cycle, and these interactions are either exploitative or antagonistic in nature. The host factors involve...Continue Reading

References

Sep 13, 2002·The Journal of Biological Chemistry·Fumitaka MomoseKyosuke Nagata
Nov 24, 2006·Journal of Virology·Tadasuke NaitoKyosuke Nagata
Nov 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Tadasuke NaitoKyosuke Nagata
Apr 1, 2008·Trends in Microbiology·John M NichollsJ S Malik Peiris
Apr 3, 2008·Reviews in Medical Virology·Kyosuke NagataTadasuke Naito
Mar 18, 2009·Cellular Microbiology·Christina Ehrhardt, Stephan Ludwig
Dec 8, 2009·Science·Jan E CaretteThijn R Brummelkamp
Dec 23, 2009·Nature·Renate KönigSumit K Chanda
Jan 12, 2010·Current Opinion in Immunology·Courtney Wilkins, Michael Gale
Jun 15, 2010·Cell Host & Microbe·Tokiko WatanabeYoshihiro Kawaoka
Jun 25, 2010·Journal of Virology·Tatiana FislováErvin Fodor
Jul 16, 2010·Reviews in Medical Virology·Stephanie BertramStefan Pöhlmann
Aug 13, 2010·Journal of Virology·Kevin M CoombsEarl G Brown
Feb 1, 2011·Microbes and Infection·Christopher D O'Donnell, Kanta Subbarao
Feb 19, 2011·Current Opinion in Infectious Diseases·Shuhua WuWenxin Wu
Jul 29, 2011·Journal of Virology·Mei-Lin YangAi-Li Shiau
Aug 16, 2011·Current Opinion in Immunology·Satoshi Fukuyama, Yoshihiro Kawaoka
Oct 4, 2011·Virus Research·J H C M KreijtzG F Rimmelzwaan
Feb 1, 2012·Cellular Microbiology·Dimiter DemirovStephan Ludwig
Mar 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Takeo GoraiYoshihiro Kawaoka
Jun 15, 2012·Journal of Virology·Dorothée MoisyJean-Luc Jestin
Dec 15, 2012·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Patricia Resa-Infante, Gülsah Gabriel
Dec 21, 2012·Journal of Virology·Eileen SunXiaowei Zhuang
Oct 9, 2013·Proceedings of the National Academy of Sciences of the United States of America·Wen-Chi SuMichael M C Lai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Science China. Life Sciences
XinXian DaiTao Hong
Journal of Microbiology and Biotechnology
Chang Woo HanSe Bok Jang
Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
E G Brown
© 2021 Meta ULC. All rights reserved