Host-parasite interactions and the evolution of ploidy

Proceedings of the National Academy of Sciences of the United States of America
Scott L Nuismer, S P Otto

Abstract

Although the majority of animals and plants, including humans, are dominated by the diploid phase of their life cycle, extensive diversity in ploidy level exists among eukaryotes, with some groups being primarily haploid whereas others alternate between haploid and diploid phases. Previous theory has illuminated conditions that favor the evolution of increased or decreased ploidy but has shed little light on which species should be primarily haploid and which primarily diploid. Here, we report a discovery that emerged from host-parasite models in which ploidy levels were allowed to evolve: selection is more likely to favor diploidy in host species and haploidy in parasite species. Essentially, when parasites must evade a host's immune system or defense response, selection favors parasitic individuals that express a narrow array of antigens and elicitors, thus favoring haploid parasites over diploid parasites. Conversely, when hosts must recognize a parasite before mounting a defensive response, selection favors hosts with a broader arsenal of recognition molecules, thus favoring diploid hosts over haploid hosts. These results are consistent with the predominance of haploidy among parasitic protists.

References

Jul 1, 1992·Genetics·S P Otto, D B Goldstein
May 23, 1991·Nature·V PerrotM Valéro
Nov 29, 1994·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J Klein, C O'Huigin
Nov 29, 1994·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A L HughesM Nei
Apr 7, 1995·The Journal of Biological Chemistry·J E Donelson
Apr 1, 1994·Genetics·H A Orr, S P Otto
Jul 22, 1997·Proceedings of the National Academy of Sciences of the United States of America·M NeiT Sitnikova
Jun 30, 2000·Current Opinion in Plant Biology·N D Young
Feb 13, 2001·Molecular and Biochemical Parasitology·S E MelvilleG A Cross
Apr 25, 2001·The Journal of Membrane Biology·J Kusch, H J Schmidt
Aug 28, 2002·Genetics·Mark KirkpatrickNick Barton
Mar 15, 2003·Science·Peter H Thrall, Jeremy J Burdon

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Citations

Aug 6, 2008·Immunogenetics·Elise HuchardLeslie A Knapp
Feb 9, 2008·Molecular Biology and Evolution·Laura Wegener ParfreyLaura A Katz
Jan 20, 2012·Biology Letters·K C KingM Neiman
Aug 10, 2005·Proceedings. Biological Sciences·Ruth HamiltonSteve Paterson
Feb 4, 2011·Proceedings. Biological Sciences·Leithen K M'Gonigle, Sarah P Otto
Jul 17, 2007·BMC Evolutionary Biology·Isabel Gordo, Paulo R A Campos
May 26, 2005·PLoS Biology·Scott L Nuismer, Sarah P Otto
May 31, 2006·PLoS Pathogens·Nat F BrownB Brett Finlay
Nov 14, 2012·Annual Review of Genetics·Matthew D Daugherty, Harmit S Malik
Jan 23, 2016·Evolution; International Journal of Organic Evolution·Scott L Nuismer, Mark F Dybdahl
Oct 28, 2008·The American Naturalist·Mark F DybdahlCurtis M Lively
Jan 6, 2009·The American Naturalist·John N Thompson
Jun 17, 2008·Current Opinion in Microbiology·Dieter Ebert
Jun 16, 2009·Molecular Ecology·C EizaguirreM Milinski
Jun 30, 2007·Evolution; International Journal of Organic Evolution·Luke G BarrettJeremy J Burdon
Sep 13, 2008·Evolution; International Journal of Organic Evolution·Sergey Gavrilets, Yannis Michalakis
Jan 13, 2006·Journal of Evolutionary Biology·E E Osnas, C M Lively
Jul 5, 2006·Evolution; International Journal of Organic Evolution·David W Hall, Mark Kirkpatrick
Mar 30, 2006·Evolution; International Journal of Organic Evolution·Scott L Nuismer
Sep 16, 2006·Ecology Letters·Curtis M Lively
Jun 5, 2008·Ecology Letters·Scott L NuismerFrançois Blanquart
Jan 30, 2013·Evolution; International Journal of Organic Evolution·Scott L NuismerJordi Bascompte
Mar 30, 2010·Journal of Evolutionary Biology·A W ParkY Michalakis
Oct 15, 2013·Ecology Letters·Ellen DecaesteckerJoost A M Raeymaekers
Aug 8, 2015·Journal of Theoretical Biology·Kazuhiro BesshoTroy Day
Dec 26, 2008·Current Biology : CB·Sarah P Otto, Aleeza C Gerstein
Jan 25, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Peter C ThompsonMatthew P Hare
Mar 17, 2015·PLoS Genetics·Jacob A TennessenMichael S Blouin
Sep 15, 2017·Ecology and Evolution·Scott L NuismerMark F Dybdahl
Sep 22, 2020·Ecology and Evolution·Dorian J FeistelMeleah A Hickman
Dec 20, 2020·Theoretical Population Biology·Ailene MacPhersonSarah P Otto
Dec 21, 2019·International Journal for Parasitology·Larissa CalarcoJohn Ellis

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