Hounsfield unit values of liver pathologies in unenhanced post-mortem computed tomography.

International Journal of Legal Medicine
Carmen TischWolf-Dieter Zech

Abstract

The goal of this study was to evaluate if unenhanced PMCT HU values of liver pathologies differ from post-mortem HU values of non-pathologic liver tissue. Liver HU values were measured in five liver segments in PMCT unenhanced datasets of 214 forensic cases (124 male, 90 female, mean age 54.3 years). Liver HU values were compared with corresponding histologic liver findings. HU values of non-pathologic livers were compared to HU values of liver pathologies. A total of 64 non-pathologic livers (mean HU 58.32, SD 8.91) were assessed. Histologic diagnosed liver pathologies were as follows: steatosis (n = 121 (grade I n = 61, grade II n = 37, grade III n = 23)), fibrosis (n = 10), and cirrhosis (n = 19). HU values of the livers exhibiting severe steatosis (mean HU 32.44, SD 13.76), fibrosis (mean HU 44.7, SD 16.31), and cirrhosis (mean HU 50.59, SD 9.42) significantly differed to HU values of non-pathologic livers at ANOVA testing. PMCT unenhanced liver HU value measurements may be used as an additional method to detect unspecific liver-pathology. Values below 30 HU may specifically indicate severe steatosis.

References

Aug 1, 1979·Journal of Computer Assisted Tomography·G M Bydder, L Kreel
Apr 1, 1980·Journal of Computer Assisted Tomography·G M Bydder, L Kreel
Mar 3, 2004·Radiology·Delphine ZeitounValérie Vilgrain
Oct 11, 2005·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Elizabeth M Brunt
Nov 15, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Okka W HamerClaude B Sirlin
Apr 24, 2007·AJR. American Journal of Roentgenology·Yoshihisa KodamaChusilp Charnsangavej
Apr 4, 2009·Legal Medicine·Hajime YokotaHisao Ito
Feb 23, 2010·AJR. American Journal of Roentgenology·Cody J BoyceJ Louis Hinshaw
Mar 10, 2012·International Journal of Legal Medicine·C EggerS Grabherr
Mar 21, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Claes LundströmAnders Ynnerman
Apr 27, 2012·Forensic Science International : Synergy·Thomas D RuderGary M Hatch
Jun 23, 2012·Forensic Science International : Synergy·Florin T F GebhartTanja Germerott
Mar 26, 2014·AJR. American Journal of Roentgenology·Patricia M FlachTanja Germerott
Jun 7, 2014·International Journal of Legal Medicine·Wolf-Dieter ZechLevent Kara
Dec 3, 2014·Biochimica Et Biophysica Acta·Shaina AilawadiGuo-Chang Fan
Sep 25, 2015·International Journal of Legal Medicine·Wolf-Dieter ZechPaolo Lombardo
Jul 26, 2016·Canadian Journal of Gastroenterology & Hepatology·Malcolm M WellsJeffery Bird
Oct 22, 2016·International Journal of Legal Medicine·Daniel SchoberChristian Jackowski
May 18, 2017·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Anthony C KlopRoelof-Jan Oostra

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