House Dust Mite Respiratory Allergy: An Overview of Current Therapeutic Strategies

The Journal of Allergy and Clinical Immunology. in Practice
Moises A CalderonPascal Demoly

Abstract

Although house dust mite (HDM) allergy is a major cause of respiratory allergic disease, specific diagnosis and effective treatment both present unresolved challenges. Guidelines for the treatment of allergic rhinitis and asthma are well supported in the literature, but specific evidence on the efficacy of pharmacotherapy treatment for known HDM-allergic patients is weaker. The standard diagnostic techniques--skin prick test and specific IgE testing--can be confounded by cross-reactivity. However, component-resolved diagnosis using purified and recombinant allergens can improve the accuracy of specific IgE testing, but availability is limited. Treatment options for HDM allergy are limited and include HDM avoidance, which is widely recommended as a strategy, although evidence for its efficacy is variable. Clinical efficacy of pharmacotherapy is well documented; however, symptom relief does not extend beyond the end of treatment. Finally, allergen immunotherapy has a poor but improving evidence base (notably on sublingual tablets) and its benefits last after treatment ends. This review identifies needs for deeper physician knowledge on the extent and impact of HDM allergy in respiratory disease, as well as further development and...Continue Reading

References

Feb 26, 1999·BMJ : British Medical Journal·P G ShekelleJ Grimshaw
Jun 26, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R ValentaH Grönlund
Feb 25, 2000·BMJ : British Medical Journal·A R JadadR Stevens
Jul 26, 2002·Psychosomatic Medicine·Paul S MarshallPaul Steinberg
Aug 24, 2002·BMJ : British Medical Journal·Mahmoud ZureikUNKNOWN European Community Respiratory Health Survey
Feb 13, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·V Di RienzoG Passalacqua
Mar 26, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A JaénUNKNOWN European Community Respiratory Health Survey
Jul 24, 2003·International Archives of Allergy and Immunology·Mitsuaki KimuraTakami Yoshida
Feb 26, 2004·Allergy·F FerreiraA Mari
Apr 22, 2004·The Journal of Allergy and Clinical Immunology·Allan BeckerMoira Chan-Yeung
May 6, 2004·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Susanne Halken
Jun 24, 2004·Archives of Disease in Childhood·S Miceli SopoS Tripodi
Aug 13, 2004·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Iwona StelmachPiotr Kuna
Oct 14, 2004·The Journal of Allergy and Clinical Immunology·Claus BachertUNKNOWN XPERT Study Group
Nov 2, 2004·The European Respiratory Journal·V Bauchau, S R Durham
Feb 12, 2005·Current Medical Research and Opinion·Michael S Blaiss, UNKNOWN Allergic Rhinitis in Schoolchildren Consensus Group
Jul 2, 2005·The Journal of Allergy and Clinical Immunology·Moira Chan-YeungAllan Becker
Jul 12, 2005·Respiratory Medicine·Hendrik NolteVibeke Backer
Jan 3, 2006·The Journal of Allergy and Clinical Immunology·Jean BousquetBashar Allaf
Sep 5, 2006·The Journal of Allergy and Clinical Immunology·Matias TorrentJosep Maria Anto
Dec 15, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Carah B SantosTimothy J Craig
Dec 22, 2006·Drugs·Jeffrey M Lehman, Michael S Blaiss
Feb 13, 2007·The Journal of Allergy and Clinical Immunology·Syed Hasan ArshadSharon M Matthews
Dec 6, 2007·Allergy·G W CanonicaJ C Virchow
Feb 14, 2008·The Journal of Allergy and Clinical Immunology·Jonathan CorrenAlkis Togias
Apr 15, 2008·Pulmonary Pharmacology & Therapeutics·Kristina UlrichSteven M Evans
Apr 19, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M G Stewart
May 1, 2008·Allergy·P C Gøtzsche, H K Johansen
May 16, 2008·American Journal of Respiratory and Critical Care Medicine·Pranab HaldarRuth H Green
Jul 31, 2008·The Journal of Allergy and Clinical Immunology·Dana V WallaceUNKNOWN Joint Council of Allergy, Asthma and Immunology

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Citations

Jan 7, 2016·Expert Opinion on Emerging Drugs·Amelia LicariGiorgio Ciprandi
May 28, 2016·Expert Review of Respiratory Medicine·Sejal Saglani, Louise Fleming
Nov 8, 2016·The Journal of Allergy and Clinical Immunology·Robert K Bush
Oct 21, 2016·Expert Review of Clinical Immunology·Pascal DemolyKarl-Christian Bergmann
Apr 30, 2017·The World Allergy Organization Journal·Mario Sánchez-BorgesArnaldo Capriles-Hulett
Jun 28, 2017·International Journal of Molecular Sciences·Manuel Reithofer, Beatrice Jahn-Schmid
Mar 24, 2018·Immunotherapy·Wenming ZhangKari Nadeau
Dec 3, 2016·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tibor Z VeresRonald N Germain
Apr 28, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K H ParkJ-W Park
Oct 23, 2019·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Plamena NovakovaSilviya Novakova
Jul 20, 2019·Current Protein & Peptide Science·Qing XiongStephen Kwok-Wing Tsui
Jun 28, 2018·Clinical and Translational Allergy·Ying ZhouJun Qian
Apr 22, 2017·Current Allergy and Asthma Reports·Daniela PosaPaolo Maria Matricardi
Aug 22, 2018·Current Allergy and Asthma Reports·Paivi M SaloDarryl C Zeldin
Mar 27, 2019·Allergy, Asthma & Immunology Research·Sung Ryeol KimJung Won Park
Jun 14, 2020·Science Immunology·Grégory SeumoisPandurangan Vijayanand
Oct 6, 2020·American Journal of Rhinology & Allergy·Kijeong LeeTae Hoon Kim
Jan 26, 2021·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Angelica TiotiuFulvio Braido
Mar 16, 2021·The World Allergy Organization Journal·Sara HuberPeter Briza
Mar 28, 2021·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Lubnaa HossenbaccusAnne K Ellis
Feb 25, 2019·The Journal of Allergy and Clinical Immunology. in Practice·Moises A CalderónPascal Demoly
May 26, 2021·Expert Review of Respiratory Medicine·Angelica TiotiuFulvio Braido
Jul 9, 2021·Frontiers in Microbiology·Dominika Jakubczyk, Sabina Górska

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