PMID: 8589520Aug 1, 1995Paper

How bats achieve a small C-value: frequency of repetitive DNA in Macrotus

Mammalian Genome : Official Journal of the International Mammalian Genome Society
R A Van Den BusscheR J Baker

Abstract

Bats possess a genome approximately 50-87% the size of other eutherian mammals. We document that the events that have achieved or maintained a small genome size in the Mexican leaf-nosed bat Macrotus waterhousii have resulted in a lower copy number of interspersed and tandemly repetitive elements. These conclusions are based on examination of 1726 randomly chosen recombinant cosmids, with an average insert size of 35.7 kb and representing 2.6% of the haploid genome of M. waterhousii. Probes representative of microsatellites [(GT)n, (CT)n, (AT)n, (GC)n] and a tandem repeat (rDNA) were used to estimate frequency of repetitive elements in the M. waterhousii genome. Of the four dinucleotides, (GT)n was present in 33.5% of the clones, (CT)n was present in 31.0% of the clones, and (AT)n and (GC)n were not represented in any of the clones examined. The 28S rDNA and a repetitive element from M. californicus were found in three and four clones, respectively. The dinucleotides (GT)n and (CT)n occurred together in the same clone more frequently than expected from chance. Although our data do not allow us to empirically test which mechanisms are maintaining copy number of repetitive DNA in the bat genome, the nonrandom association of these...Continue Reading

References

Apr 1, 1992·Genomics·J S Beckman, J L Weber
Sep 1, 1991·The Journal of Heredity·T R Tiersch, S S Wachtel
May 23, 1985·Nature·T Cavalier-Smith
Oct 1, 1974·Biochemical Genetics·R B FlavellD B Smith
Jan 1, 1972·Chromosoma·K Bachmann
Nov 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·H HamadaT Kakunaga
Jun 1, 1993·Genetic Analysis, Techniques and Applications·J L LongmireG A Evans
Jan 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·L L JanecekR J Baker
Nov 1, 1950·Proceedings of the National Academy of Sciences of the United States of America·H SWIFT
Jul 1, 1989·Evolution; International Journal of Organic Evolution·David W BurtonHugh H Genoways

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Citations

Jul 25, 2013·Chromosoma·Fumio KasaiMalcolm A Ferguson-Smith
Aug 30, 2012·Genome Biology and Evolution·Qu Zhang, Scott V Edwards
Sep 4, 2008·Proceedings. Biological Sciences·Chandler B AndrewsT Ryan Gregory
Oct 30, 2001·Evolution; International Journal of Organic Evolution·B D Neff, M R Gross
Mar 27, 2002·Evolution; International Journal of Organic Evolution·T Ryan Gregory
Nov 18, 2000·Genome Génome / Conseil National De Recherches Canada·T R Gregory
Feb 28, 2008·BMC Evolutionary Biology·Neil D TsutsuiJ Spencer Johnston
Jan 19, 2008·Genetics·Michael A CantrellHolly A Wichman
Mar 3, 1999·Molecular Phylogenetics and Evolution·R A Van Den BusscheD M Hillis
Jul 5, 2005·The Journal of Heredity·C A RediE Capanna
Oct 14, 2017·Genes·Cibele G Sotero-CaioMarianne Volleth
Jan 7, 2004·Nature Reviews. Molecular Cell Biology·Michael R Lieber, Zarir E Karanjawala
Mar 9, 2007·Nature·Chris L OrganScott V Edwards
May 26, 2012·Cytogenetic and Genome Research·C A Redi, E Capanna
Mar 5, 2009·Bioinspiration & Biomimetics·Anders HedenströmGeoffrey R Spedding
May 1, 1997·Genome Research·C R PrimmerH Ellegren

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