Jan 15, 2016

How clonal are bacteria over time?

BioRxiv : the Preprint Server for Biology
B Jesse Shapiro

Abstract

Bacteria and archaea reproduce clonally (vertically), but exchange genes by recombination (horizontal transfer). Recombination allows adaptive mutations or genes to spread within (or between) species. Clonality - the balance between vertical and horizontal inheritance - is therefore a key microbial trait, determining how quickly a population can adapt. Here, I consider whether clonality can be considered a stable trait of a given population. In some cases, clonality changes over time: non-clonal (recombining) populations can give rise to clonal expansions. However, an analysis of time-course metagenomic data suggests that a bacterial population's past clonality is indicative of its future clonality. Thus, a population's evolutionary potential - whether it is likely to retain genetic diversity or not - can in principle be predicted from its past.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Genes
Recombination, Genetic
Archaea
Genetic Inheritance
Clone
Cell Growth
Microbial
Species
Analysis
Horizontal

About this Paper

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

Current Opinion in Microbiology
B Jesse Shapiro
Journal of Computational Biology : a Journal of Computational Molecular Cell Biology
Sergey PirogovMikhail Gelfand
BioRxiv : the Preprint Server for Biology
Jennifer Crodelle, D. W. McLaughlin
Enfermedades infecciosas y microbiología clínica
G Prats
© 2020 Meta ULC. All rights reserved