How closely do blood gas electrolytes and haemoglobin agree with serum values in adult emergency department patients: An observational study

Emergency Medicine Australasia : EMA
Michael GibbonsAnne-Maree Kelly

Abstract

The aims of this study were to establish the bias (mean difference) and 95% limits of agreement (LoA) between electrolyte values (sodium and potassium) and haemoglobin between whole blood analysed by the ED resuscitation room blood gas analyser and specimens analysed using standard techniques in the central hospital laboratory and to determine the proportion of analyses falling outside defined clinically acceptable LoA and pathology expert defined standards. Prospective cohort study. Paired blood gas analyser and laboratory samples taken no more than 10 min apart were included. The primary outcome of interest was bias and 95% LoA by Bland-Altman analysis. Subgroup analyses for values outside the normal range were also conducted. Three hundred and fifty-two sample pairs were included in the analysis. For sodium concentration the bias was 0.6 mmol/L (95% LoA -3.3 to 4.6 mmol/L). For potassium concentration the bias was 0.21 mmol/L (95% LoA -0.36 to 0.79 mmol/L). For haemoglobin concentration the bias was -1.6 g/dL (95% LoA -10.2 to 6.9 g/dL). For sodium and haemoglobin concentrations, >95% of results fell within the defined clinically acceptable limits. For potassium concentration, >90% of results fell within the defined clinical...Continue Reading

References

Feb 17, 2010·International Journal of Emergency Medicine·Anunaya JainMahesh Joshi
Aug 29, 2013·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Benjamin M BloomTim Harris
Nov 29, 2014·Scandinavian Journal of Clinical and Laboratory Investigation·Metin UyanikIsmail Kurt
Jun 16, 2016·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Shalini GuptaMinni Verma
May 10, 2017·Heart & Lung : the Journal of Critical Care·Alexandra Gavala, Pavlos Myrianthefs

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Citations

Jul 11, 2020·Archives of Pathology & Laboratory Medicine·Ana Laila Qasem MorenoAntonio Buño Soto
Oct 15, 2020·Archives of Pathology & Laboratory Medicine·Hyung-Doo Park

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