How do frozen and permanent histopathologic diagnoses compare for staged revision after periprosthetic hip infections?

The Journal of Arthroplasty
D Alex StrohMichael A Mont

Abstract

Histopathologic analysis of frozen tissue samples is used to aid the intraoperative diagnosis of periprosthetic hip infections, but there are concerns about reliability. The purposes of this study were to determine the rate of concordance between diagnoses of infection made with frozen and permanent sections and to assess how discrepancies affected patient outcomes. A total of 282 samples from 62 patients were collected for frozen and permanent section analysis. There was concordance in 274 samples (97%). In 1 case, discrepancies led to retention of components during persistent infection, and the patient required further revision and antibiotics until infection free. Otherwise, discrepancies did not affect patient outcomes. There is good concordance between frozen and permanent sections for diagnosing periprosthetic hip infection and rarely do these discrepancies affect management.

References

Jul 31, 1999·The Journal of Arthroplasty·C J Della ValleP E Di Cesare
Nov 13, 2003·Postgraduate Medical Journal·A D MussoR Spencer-Jones
Oct 7, 2004·The American Journal of Medicine·Andrej TrampuzRobin Patel
Dec 27, 2005·The Journal of Arthroplasty·Yiu-Chung WongWai-Fu Ng
Apr 6, 2006·The Journal of Bone and Joint Surgery. American Volume·Thomas W BauerViktor Krebs
Jun 27, 2006·The Journal of Bone and Joint Surgery. British Volume·J E PhillipsR J Grimer
Aug 15, 2008·American Journal of Clinical Pathology·William A KannerHenry F Frierson
May 29, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Elie GhanemJavad Parvizi

❮ Previous
Next ❯

Citations

Apr 9, 2013·BMC Musculoskeletal Disorders·Aaron J JohnsonMichael A Mont
Dec 18, 2013·The Journal of Arthroplasty·Benjamin ZmistowskiEivind Witzo
Jan 28, 2014·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Benjamin ZmistowskiEivind Witzo
Apr 3, 2016·The Journal of Arthroplasty·Mansour AbolghasemianDavid J Backstein
Jul 28, 2016·The Journal of Arthroplasty·Grzegorz KwiecienCarlos A Higuera Rueda
Jun 17, 2020·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Lucas LuyckxLore Hermans
Jan 1, 2021·The Bone & Joint Journal·Martin McNallyRihard Trebše
Jul 22, 2019·The Journal of Arthroplasty·Anas SalehCarlos A Higuera-Rueda
May 28, 2021·EFORT Open Reviews·Pier F IndelliDerek F Amanatullah

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.