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How do SNP ascertainment schemes and population demographics affect inferences about population history?

BMC Genomics

Apr 19, 2015

Emily Jane McTavish, David M Hillis

Abstract

The selection of variable sites for inclusion in genomic analyses can influence results, especially when exemplar populations are used to determine polymorphic sites. We tested the impact of ascertainment bias on the inference of population genetic parameters using empirical and simulat...read more

Mentioned in this Paper

Gene Polymorphism
Genome
Complement Component 2 Deficiency
Genetics, Population
Bos taurus
Weighing Patient
Patient Care
Site
Genomics
Comparative Genomic Analysis
7
87
Paper Details
References
  • References64
  • Citations11
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  • References64
  • Citations11
12

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How do SNP ascertainment schemes and population demographics affect inferences about population history?

BMC Genomics

Apr 19, 2015

Emily Jane McTavish, David M Hillis

PMID: 25887858

DOI: 10.1186/s12864-015-1469-5

Abstract

The selection of variable sites for inclusion in genomic analyses can influence results, especially when exemplar populations are used to determine polymorphic sites. We tested the impact of ascertainment bias on the inference of population genetic parameters using empirical and simulat...read more

Mentioned in this Paper

Gene Polymorphism
Genome
Complement Component 2 Deficiency
Genetics, Population
Bos taurus
Weighing Patient
Patient Care
Site
Genomics
Comparative Genomic Analysis
7
87

Feeds With Similar Papers

Perturb-seq

Perturb-seq has combined CRISPR gene inactivation and single-cell rna-sequencing (scRNA-seq) and is the newest addition to the geneticist's arsenal, providing scientists with study methods for functional genomics. Discover the latest research here.

Comparative Sequencing

Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

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Paper Details
References
  • References64
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