How do women of diverse backgrounds value prenatal testing outcomes?

Prenatal Diagnosis
Miriam KuppermannA Eugene Washington

Abstract

To describe women's preferences for prenatal testing outcomes and to explore their association with sociodemographic characteristics and attitudes. We conducted a cross-sectional study of 584 racially/ethnically and socioeconomically diverse pregnant women aged 16 to 47 years recruited from 23 San Francisco Bay Area practices. We assessed preferences for 12 potential prenatal testing outcomes using the time trade-off metric for all outcomes and the standard gamble metric for two outcomes. Preferences were calculated on a scale of 0 (death) to 1 (perfect health). Participants also completed a sociodemographic and attitude survey. Highest preference scores were assigned to outcomes resulting in the birth of a chromosomally normal infant (mean = 0.91-0.93; median = 0.99-1.00). Lower scores were obtained for outcomes involving pregnancy loss (mean = 0.69-0.87; median = 0.76-0.92), which were correlated with attitudes regarding miscarriage, pregnancy termination, and Down syndrome. The lowest scores were assigned to Down syndrome-affected births (mean = 0.67-0.69; median = 0.73-0.75), which also were correlated with attitudes toward Down syndrome. We did not find a statistically significant relationship between participants' prefere...Continue Reading

Citations

Sep 6, 2008·Human Reproduction Update·M A DurandG Elwyn
Feb 16, 2005·Gynecologic and Obstetric Investigation·Miriam Kuppermann, Mary E Norton
Nov 2, 2006·American Journal of Public Health·Babak KhoshnoodBéatrice Blondel
Mar 11, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·M-C GrupposoB Blondel
Jun 4, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·B KhoshnoodF Goffinet
Oct 21, 2009·Prenatal Diagnosis·Mirjam P FransenMarie-Louise Essink-Bot
Sep 13, 2013·Prenatal Diagnosis·Brandon WalkerDanielle Lagrave
Jan 8, 2008·American Journal of Obstetrics and Gynecology·Aaron B CaugheyMiriam Kuppermann
May 2, 2006·Obstetrics and Gynecology·Miriam KuppermannA Eugene Washington
Jul 14, 2006·Prenatal Diagnosis·Nedra S WhiteheadSamuel F Posner
Jun 15, 2007·Mental Retardation and Developmental Disabilities Research Reviews·Kelly M MungerKristi L Kirschner
Jun 1, 2005·The Journal of Perinatal & Neonatal Nursing·Lisa Zindler

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