How Does Bone Strength Compare Across Sex, Site, and Ethnicity?

Clinical Orthopaedics and Related Research
Stephen H SchlechtKarl J Jepsen

Abstract

The risk of fragility fractures in the United States is approximately 2.5 times greater among black and white women compared with their male counterparts. On average, men of both ethnicities have wider bones of greater cortical mass compared with the narrower bones of lower cortical mass among women. However, it remains uncertain whether the low cortical area observed in the long bones of women is consistent with their narrower bone diameter or if their cortical area is reduced beyond that which is expected for the sex differences in body size and external bone size. We asked (1) do black and white women consistently have narrower bones of less strength across long bones compared with black and white men; and (2) do all long bones of black and white women have reduced cortical area compared with black and white men? Peripheral quantitative CT was used to quantify bone strength and cross-sectional morphology from the major long bones of 125 white and 115 black adult men and women (20-35 years of age). Regression analyses were used to test for differences in bone strength and cortical area after for adjusting for either body size, bone size, or both. After adjusting bone strength for body size, regression analyses showed that bla...Continue Reading

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Citations

Nov 18, 2016·The Journal of the American Academy of Orthopaedic Surgeons·Col Jeffrey N Davila, Andrew H Schmidt
Jan 14, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Karl J JepsenCarrie Karvonen-Gutierrez
Sep 12, 2017·International Journal of Environmental Research and Public Health·Xinge ZhangGuoxun Chen
Jul 10, 2019·Traffic Injury Prevention·Jason FormanCecilia Sunnevang
Feb 1, 2020·Expert Opinion on Pharmacotherapy·Sunny TrivediC Thomas Vangsness
Aug 6, 2020·Frontiers in Cell and Developmental Biology·Chunli WangLinlin Hao
Nov 15, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A MaganJ M Pettifor

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