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How does chondroitinase promote functional recovery in the damaged CNS?

Experimental Neurology

Jun 19, 2007

Dámaso CrespoJames W Fawcett

Abstract

A number of recent studies have established that the bacterial enzyme chondroitinase ABC promotes functional recovery in the injured CNS. The issue of how it works is rarely addressed, however. The effects of the enzyme are presumed to be due to the degradation of inhibitory chondroitin...read more

Mentioned in this Paper

Buffers
Immune Response
Biochemical Pathway
Chondroitin
Keratan Sulfate
Calcium [EPC]
Meninges
Immunoreactivity
Extracellular
Angiogenic Process
107
Paper Details
References
  • References108
  • Citations72
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  • References108
  • Citations72
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How does chondroitinase promote functional recovery in the damaged CNS?

Experimental Neurology

Jun 19, 2007

Dámaso CrespoJames W Fawcett

PMID: 17572406

DOI: 10.1016/j.expneurol.2007.05.001

Abstract

A number of recent studies have established that the bacterial enzyme chondroitinase ABC promotes functional recovery in the injured CNS. The issue of how it works is rarely addressed, however. The effects of the enzyme are presumed to be due to the degradation of inhibitory chondroitin...read more

Mentioned in this Paper

Buffers
Immune Response
Biochemical Pathway
Chondroitin
Keratan Sulfate
Calcium [EPC]
Meninges
Immunoreactivity
Extracellular
Angiogenic Process
107

Similar Papers Found In These Feeds

Astrocytes and Neurodegeneration

Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.

Molecular Organization of Synapses

This feed focuses on the molecular organization of synapses between two nerve cells, synaptic signal transduction, and synaptic vesicles. Here is the latest research on organization of synapses.

Related Papers

Paper Details
References
  • References108
  • Citations72
12345...
  • References108
  • Citations72
12345...
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