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How does chondroitinase promote functional recovery in the damaged CNS?

Experimental Neurology

Aug 1, 2007

Dámaso CrespoJames W Fawcett

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Abstract

A number of recent studies have established that the bacterial enzyme chondroitinase ABC promotes functional recovery in the injured CNS. The issue of how it works is rarely addressed, however. The effects of the enzyme are presumed to be due to the degradation of inhibitory chondroitin...read more

Mentioned in this Paper

Proteoglycan
Cell Secretion
Enzymes, antithrombotic
Lyase
White Matter
Recovery of Function
Proteolytic Enzyme
Motility
Angiogenic Process
Enzymes, peripheral vasodilators
104
Paper Details
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    • References108
    • Citations62
    • References108
    • Citations62
  • How does chondroitinase promote functional recovery in the damaged CNS?

    Experimental Neurology

    Aug 1, 2007

    Dámaso CrespoJames W Fawcett

    PMID: 17572406

    DOI: 10.1016/j.expneurol.2007.05.001

    Abstract

    A number of recent studies have established that the bacterial enzyme chondroitinase ABC promotes functional recovery in the injured CNS. The issue of how it works is rarely addressed, however. The effects of the enzyme are presumed to be due to the degradation of inhibitory chondroitin...read more

    Mentioned in this Paper

    Proteoglycan
    Cell Secretion
    Enzymes, antithrombotic
    Lyase
    White Matter
    104

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    Paper Details
    References
    • References108
    • Citations62
    • References108
    • Citations62
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