How does the pattern of aeroallergen sensitization change over time across all ages?

International Forum of Allergy & Rhinology
Ji-Hyeon Shin, Dong-Hee Lee

Abstract

Identification of aeroallergen sensitization is important for diagnosis and management of allergic diseases. Immunoglobulin E (IgE) sensitization status is known to change over time. However, few studies have explored changes in sensitization patterns across all age groups. The aim of the present study was to evaluate the changing patterns of in vitro IgE sensitization tests in allergic rhinitis patients across all age groups. We recruited all patients who were diagnosed as having rhinitis and who underwent in vitro IgE sensitization testing from 2007 to 2016. Of these, we included 138 who underwent repeat testing. We analyzed epidemiological data and allergen sensitization patterns. Of all patients, 56.5% of exhibited changes in allergen sensitization patterns. The allergens to which all age groups were sensitive were most commonly mites, with the exception of patients aged 40 to 59 years. The age group in which "new sensitization," composed of those with "newly developed sensitization" and "sensitization to more allergens," was most frequent was the 2 to 12 years old group, followed by the 20 to 39 years old group. The age group in which "desensitization," composed of those with "negative conversion" and "desensitization to f...Continue Reading

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Citations

Jul 6, 2017·International Forum of Allergy & Rhinology·Brent A Senior
Jan 21, 2021·Expert Review of Clinical Immunology·Giorgio Ciprandi, Maria Angela Tosca
Jul 7, 2020·Clinical and Experimental Otorhinolaryngology·Dong-Kyu KimSeok Hyun Cho
May 20, 2019·International Archives of Allergy and Immunology·Zhuang-Gui ChenQin-Tai Yang

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