Jan 1, 1977

'How frequent is posttranfusion hepatitis after the introduction of 3rd generation donor screening for hepatitis B? What is its probable nature?

Vox Sanguinis


Third generation donor screening for hepatitis B is not generally efficacious in reducing PTH B except under certain epidemiological conditions. The nature of the remaining cases of PTH varies from region to region and depends on actual epidemiological circumstances. Cases of HB, transmitted by HBsAg-negative but nevertheless HBV-infectious blood, should be considered as well as cases of HB, transmitted by vehicles other than transfusion-blood, but confusingly also classified as PTH. Hepatitis A and hepatitis due to agents not yet identified occurring in blood recipients need further investigation. In such cases it remains an open question too, whether the disease is mainly transmitted with the transfusion-blood or by other vehicles, associated with large and long-lasting wounds or hospital environments as closely as blood transfusions are.

Mentioned in this Paper

Hepatitis A
Hepatitis B antigen peptide
Hepatitis A Vaccine, Inactivated
Blood Banks
Hepatitis B Surface Antigens
Blood Transfusion
In Blood
Hepatitis B Surface Antigen Measurement
Hepatitis B Vaccine

About this Paper

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.