How important is blood pressure variability?

European Heart Journal Supplements : Journal of the European Society of Cardiology
Enrico Agabiti RoseiDamiano Rizzoni

Abstract

Arterial blood pressure (BP) is a continuous variable, with a physiology characterized by significant variability stemming from the complex interaction among haemodynamic factors, neuronal reflexes, as well as hormonal, behavioural, and environmental stimuli. The homoeostatic response accounts for the physiologic variability in BP in normotensive individuals, which is more evident in hypertensive patients. Blood pressure variability is a complex phenomenon, which could be classified in various types: very short term (beat to beat), short term (during 24 h), mid-term (day by day), long term (<5 years), and very long term (>5 years). Accurate measurement of BP variability represents a complex and often controversial endeavour, despite several methodological approaches are available. Albeit a prognostic significance has been demonstrated for some indicators of BP variability, the clinical significance of this measurement is still uncertain. In fact, none of the indicators presently available for BP variability, including early morning BP rise, substantially affects, and redefines, the cardiovascular risk of the hypertensive patient, over and beyond the mere BP values. Accordingly, in defining the cardiovascular risk, the focus sho...Continue Reading

References

Apr 1, 1982·Physiological Reviews·B Folkow
Jul 11, 2007·Journal of Hypertension·Damiano RizzoniEnrico Agabiti Rosei
Apr 12, 2013·Clinical and Experimental Pharmacology & Physiology·Kei AsayamaJan A Staessen
Apr 30, 2013·Blood Pressure·Gianfranco ParatiGrzegorz Bilo
Oct 18, 2013·Journal of Human Hypertension·G ParatiJ E Ochoa
Feb 12, 2014·Hypertension·Massimo SalvettiMaria Lorenza Muiesan
Mar 21, 2015·Current Hypertension Reports·Gianfranco ParatiGrzegorz Bilo
Nov 25, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Stefano OmboniAnatoly N Rogoza
Dec 23, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Damiano Rizzoni, Claudia Agabiti-Rosei
Dec 23, 2016·Journal of Hypertension·Giacomo PucciGiuseppe Schillaci
Mar 25, 2017·American Journal of Hypertension·Damiano RizzoniEnrico Agabiti-Rosei
Jun 7, 2018·Integrated Blood Pressure Control·Grzegorz BiloGianfranco Parati
Jun 29, 2018·International Journal of General Medicine·Veerendra Melagireppa ChadachanSajita Setia

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