How is the archaeal MCM helicase assembled at the origin? Possible mechanisms

Biochemical Society Transactions
Nozomi SakakibaraZvi Kelman

Abstract

In order for any organism to replicate its DNA, a helicase must unwind the duplex DNA in front of the replication fork. In archaea, the replicative helicase is the MCM (minichromosome maintenance) helicase. Although much is known about the biochemical properties of the MCM helicase, the mechanism of assembly at the origin of replication is unknown. In the present paper, several possible mechanisms for the loading process are described.

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Citations

Nov 26, 2014·Annual Review of Genetics·Lori M Kelman, Zvi Kelman
May 6, 2009·Molecular Microbiology·Nozomi SakakibaraZvi Kelman
Dec 14, 2011·Environmental Microbiology·Aurore GorlasClaire Geslin
Nov 19, 2011·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Sonoko IshinoYoshizumi Ishino
Apr 14, 2010·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Masaki AkitaYoshizumi Ishino
Jan 30, 2013·Biochemical Society Transactions·Zhuo LiZvi Kelman
Jan 8, 2020·Journal of Bacteriology·Lori M KelmanZvi Kelman

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