How many older people are frail? Using multiple imputation to investigate frailty in the population

Journal of the American Medical Directors Association
Kieran A McCaulLeon Flicker

Abstract

The objective of this study was to establish the extent to which frailty was associated with attrition and then compare estimates of frailty prevalence and progression estimated from the observed data to those estimated after imputation. Population-based cohort study. The Health in Men Study (HIMS) with frailty estimated at Wave 2 (2001/2004) and Wave 3 (2008) and mortality follow-up to 2010. Participants were 10,305 community-dwelling men aged 70 and older, followed for up to 10 years. Participants completed an extensive questionnaire covering functional activities and illnesses. Frailty was assessed using the FRAIL Scale and a 32-item Frailty Index. Nonresponders at Wave 3 were more likely to have been frail at Wave 2. Imputed estimates of frailty prevalence were 8% to 10% higher than those derived from the observed data. Epidemiological surveys may substantially underestimate the levels of frailty among older people in the general population. This selective nonresponse results in an overoptimistic view of aging populations, particularly for the very old.

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Citations

Oct 21, 2015·Journal of Vascular Surgery·Takuro ShirasuToshiaki Watanabe
Oct 5, 2015·Journal of the American Medical Directors Association·John E Morley, Erin V Adams
Sep 4, 2016·Journal of the American Medical Directors Association·John E Morley
Nov 5, 2016·Preventive Medicine·Osvaldo P AlmeidaLeon Flicker
Oct 27, 2016·Journal of the American Geriatrics Society·Olga TheouRenuka Visvanathan
Apr 26, 2015·The Australian and New Zealand Journal of Psychiatry·John SnowdonDaniel W O'Connor
Dec 30, 2017·BMC Oral Health·Bibhas ChakrabortySara S Metcalf
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Dec 7, 2019·Aging & Mental Health·David BickfordR Scott Mackin
Jun 18, 2021·Stroke; a Journal of Cerebral Circulation·Monique F KilkennyUNKNOWN Stroke123 Investigators and the AuSCR Consortium

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