How melanoma cells evade trail-induced apoptosis

Nature Reviews. Cancer
P Hersey, X D Zhang

Abstract

At the doses used clinically, chemotherapy is believed to kill melanoma by a final common 'mitochondrial' pathway that leads to apoptosis. Similarly, several natural defence mechanisms kill melanoma by the same pathways. A corollary to the latter is that survival of melanoma in the host is due to the development of anti-apoptotic mechanisms in melanoma cells. What are these mechanisms? And how might we bypass them to improve the treatment of melanoma?

References

Aug 1, 1991·The Journal of Investigative Dermatology·F J TefanyW H McCarthy
Aug 3, 1994·Journal of the National Cancer Institute·S A RosenbergD E White
May 31, 1996·The Journal of Biological Chemistry·R M PittiA Ashkenazi
Jun 1, 1996·Current Biology : CB·S A MarstersA Ashkenazi
Oct 6, 1997·The EMBO Journal·H WalczakC T Rauch
Feb 14, 1998·Nature Medicine·B JansenH Pehamberger
Mar 21, 1998·The Journal of Biological Chemistry·D A MartinM J Lenardo
Feb 25, 1998·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·A HåkanssonL Håkansson
Apr 17, 1999·Molecular and Cellular Biology·G A Webster, N D Perkins
Apr 20, 1999·The Journal of Experimental Medicine·T S GriffithN A Fanger
Apr 21, 1999·Current Opinion in Cell Biology·A Ashkenazi, V M Dixit
May 25, 1999·Melanoma Research·L Serrone, P Hersey
Aug 4, 1999·Immunology Today·J A TrapaniM J Smyth
Aug 10, 1999·Nature·L ChinR A DePinho
Nov 5, 1999·Current Opinion in Oncology·J A Houghton
Mar 21, 2000·Biochimica Et Biophysica Acta·M W Mayo, A S Baldwin
Mar 31, 2000·Experimental Cell Research·H Walczak, P H Krammer
Feb 7, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·X D ZhangP Hersey
Apr 20, 2000·The Journal of Investigative Dermatology·E SelzerR Kodym
Jul 26, 2000·The Journal of Cell Biology·D LechardeurG L Lukacs
Aug 5, 2000·Science·P Golstein
Aug 5, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·A KhoshnanA E Nel
Aug 15, 2000·Leukemia·M S Sheikh, A J Fornace
Aug 22, 2000·The Journal of Biological Chemistry·S M SrinivasulaE S Alnemri
Aug 31, 2000·Annual Review of Biochemistry·A StrasserV M Dixit
Oct 12, 2000·The Journal of Biological Chemistry·G M Kasof, B C Gomes

❮ Previous
Next ❯

Citations

Jun 25, 2009·Cancer Immunology, Immunotherapy : CII·Peter Hersey, Xu Dong Zhang
Oct 20, 2006·Apoptosis : an International Journal on Programmed Cell Death·Susan GillespiePeter Hersey
Apr 14, 2007·Apoptosis : an International Journal on Programmed Cell Death·Theodore O GarnettPenelope Jayne Duerksen-Hughes
May 6, 2008·Apoptosis : an International Journal on Programmed Cell Death·Geoffrey E JohnsonTom K Hei
Jun 2, 2010·Apoptosis : an International Journal on Programmed Cell Death·Zhi Gang MaoXu Dong Zhang
Dec 15, 2010·Applied Biochemistry and Biotechnology·Saeed SamarghandianSaeideh Davoodi
Oct 31, 2002·Nature Immunology·Hung T Khong, Nicholas P Restifo
Feb 8, 2006·Current Opinion in Oncology·Marie-France Demierre
Feb 24, 2007·The Journal of Clinical Investigation·Baskaran GovindarajanJack L Arbiser
Mar 23, 2012·BMC Cell Biology·Noriko YanaseJunichiro Mizuguchi
Jan 17, 2009·Medical Oncology·Antonio Romo de Vivar ChavezMichael T Lotze
Feb 14, 2013·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Clemens KreplerMeenhard Herlyn
Nov 8, 2014·International Journal of Molecular Sciences·Siddarth Chandrasekaran, Michael R King
Oct 27, 2004·Cancer Science·Hideo YagitaKo Okumura
Sep 16, 2006·Immunological Reviews·Thomas F GajewskiHelena Harlin
Apr 1, 2006·Journal of Chemotherapy·R T LimaM H Vasconcelos
Apr 26, 2014·Epigenetics : Official Journal of the DNA Methylation Society·Paula L HylandXiaohong Rose Yang
Nov 30, 2012·Cancer Biology & Therapy·Ana SlipicevicVivi Ann Flørenes
Dec 14, 2005·Biochemical and Biophysical Research Communications·You-Take OhSeung Ki Lee
Mar 10, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Seyed Hadi MousaviIraj Jafari-Anarkooli
Dec 9, 2004·Biochimica Et Biophysica Acta·Simone Fulda, Klaus-Michael Debatin
Dec 7, 2007·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Jürgen EberleLothar F Fecker
Mar 13, 2012·International Journal of Molecular Sciences·Salvador J Diaz-Cano
Nov 25, 2003·Oncogene·Shulin Wang, Wafik S El-Deiry
Jan 22, 2004·International Journal of Cancer. Journal International Du Cancer·Rui LiHong-Ming Hu
Jun 6, 2003·Oncogene·María S Soengas, Scott W Lowe
Jun 6, 2003·Oncogene·Vladimir N IvanovZe'ev Ronai
Aug 16, 2003·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Takahito HottaJunichiro Mizuguchi
Nov 24, 2005·Bioelectromagnetics·Sachiko YamaguchiShoogo Ueno
Apr 5, 2013·Journal of Cellular Biochemistry·Jiezhong ChenXu Dong Zhang
Feb 13, 2016·Advanced Healthcare Materials·Lorena García-HeviaMónica L Fanarraga
Aug 5, 2004·Current Oncology Reports·Marie-France Demierre, Glenn Merlino

❮ Previous
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