How often do prescribers include indications in drug orders? Analysis of 4 million outpatient prescriptions

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Alejandra SalazarGordon D Schiff

Abstract

To examine the extent to which outpatient clinicians currently document drug indications in prescription instructions. Free-text sigs were extracted from all outpatient prescriptions generated by the computerized prescriber order entry system of a major academic institution during a 5-year period. Natural language processing was used to identify drug indications. The data set was analyzed to determine the rates at which prescribers included indications. It was stratified by provider specialty, drug class, and specific medications, to determine how often these indications were in prescriptions for as-needed (PRN) versus non-PRN medications. During the study period, 4,356,086 prescriptions were ordered. Indications were included in 322,961 orders (7.41%). From these orders, 249,262 indications (77.18%) were written for PRN orders. Although internal medicine prescribers generated the highest number of medication orders, they included indications in only 6.26% of their prescriptions, whereas orthopedic surgery providers had the highest rate of documenting indications (33.41%). Pain was the most common indication, accounting for 30.35% of all documented indications. The drug class with the highest number of sigs-containing indicatio...Continue Reading

References

Dec 15, 2004·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Stephen D PersellTejal K Gandhi
Nov 10, 2005·JAMA : the Journal of the American Medical Association·Matthew H SamoreKurt Stevenson
Jun 18, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Tewodros EgualeRobyn Tamblyn
Oct 22, 2010·Journal of the American Medical Informatics Association : JAMIA·Kin Wah FungSuresh Srinivasan
Feb 12, 2013·Journal of the American Medical Informatics Association : JAMIA·William GalanterBruce L Lambert
May 22, 2013·Research in Social & Administrative Pharmacy : RSAP·Terri L WarholakNisha Patel
Sep 30, 2014·Patient Education and Counseling·Jennifer L KuntzMark C Hornbrook
Feb 11, 2015·Journal of the American Medical Informatics Association : JAMIA·Catherine PlaisantBen Shneiderman
Jul 28, 2016·The New England Journal of Medicine·Gordon D SchiffAdam Wright
Apr 21, 2018·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Kevin KronGordon Schiff

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Citations

Sep 3, 2020·British Journal of Clinical Pharmacology·Melissa T BaysariRichard O Day
Oct 30, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Mojtaba VaismoradiManela Glarcher

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