How often is NIDDM complicated with non-diabetic renal disease? An analysis of renal biopsies and the literature

Diabetologia
S Olsen, C E Mogensen

Abstract

According to extensive autopsy studies, non-diabetic renal disease seems to be rare in diabetes mellitus, but recent publications suggest a significant prevalence of non-diabetic renal disease in non-insulin-dependent diabetic (NIDDM) patients, especially in the absence of retinopathy. The purpose of this study was to evaluate the prevalence of non-diabetic renal disease in NIDDM patients in renal biopsies from clinical practice, in patients suspected of having non-diabetic renal disease. In addition we systematically reviewed the literature. Biopsies were evaluated at the University Department of Pathology, Aarhus, Denmark, but had been collected at several departments of nephrology. In total 33 consecutive biopsies were available from 1988-1995 (mean age of patients: 62 years (range 39-75) (mean known diabetes duration 8 years (range 1-25); the main clinical reason for a biopsy was proteinuria. Renal function changes ranged from slight elevation of serum creatinine to uraemia. In addition 9 original papers, including our own material 580 patients were examined. On the basis of careful morphological evaluation according to international criteria, no patient exhibited an unequivocal sign of non-diabetic glomerular disease. Two ...Continue Reading

Citations

Oct 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Johannes F E MannUNKNOWN HOPE Investigators
Sep 6, 2002·Diabetes Research and Clinical Practice·Assumpta SerraJosep Bonet
May 31, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Barry StokesVivette D D'Agati
Dec 13, 2000·Journal of Diabetes and Its Complications·R M Bruno, J L Gross
Jul 16, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Fernand Mac-Moune LaiKa-Fai To
Feb 13, 2001·European Journal of Clinical Investigation·M Kanauchi, K Dohi
Sep 30, 2000·Kidney International·P K ChristensenH H Parving
Jan 20, 2011·European Journal of Public Health·Chalapati RaoSuhail A R Doi
Apr 22, 2008·International Journal of Clinical Practice·Y-L LinC-S Yang
May 15, 2007·American Journal of Nephrology·Tam T PhamVictoria A Kumar
Dec 3, 2011·Journal of the American Society of Nephrology : JASN·Derek M FineKarl Skorecki
Jan 18, 2013·Indian Journal of Nephrology·U DasM S Uppin
Mar 22, 2014·Cell Biochemistry and Biophysics·Shuang LiangGuang-Yan Cai
Feb 24, 2001·Scandinavian Journal of Urology and Nephrology·C M NzerueR Oster
Jan 8, 2013·The Medical Clinics of North America·Brendan T BowmanW Kline Bolton
Sep 4, 2012·European Journal of Internal Medicine·C T PostmaTh Thien
Dec 17, 2009·Diabetes Research and Clinical Practice·Shan MouZhaohui Ni
Jan 8, 2008·Diabetes Research and Clinical Practice·Tomoya FukeAtsunori Kashiwagi
Mar 29, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Gianna MazzuccoGuido Monga
Apr 10, 2007·Seminars in Nephrology·Paola Fioretto, Michael Mauer
Nov 23, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·UNKNOWN ESRD Incidence Study GroupS M Williams
Jun 30, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·K P G Harris
Aug 21, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·M OhtaY Iwamoto
Jan 29, 2013·Journal of Diabetes Investigation·Koji HaradaYoshihiko Saito
Dec 31, 2008·The American Journal of Medicine·Mohamed G AttaTiffany L Gary
Aug 16, 2005·Diabetes Research and Clinical Practice·Atsuhito ToneHirofumi Makino
Sep 7, 2013·The Korean Journal of Internal Medicine·Cheol Whee Park
Mar 31, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Dao-Fu DaiBehzad Najafian
Jan 31, 2015·Journal of Diabetes and Its Complications·Maria PallayovaIndranil Dasgupta
Oct 17, 2003·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Elias S SirajS Sethu K Reddy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved