We examine the Tree of Life (TOL) as an evolutionary hypothesis and a heuristic. The original TOL hypothesis has failed but a new "statistical TOL hypothesis" is promising. The TOL heuristic usefully organizes data without positing fundamental evolutionary truth.
Compositional statistics: an improvement of evolutionary parsimony and its application to deep branches in the tree of life
Production and disposal of medium-chain fatty acids in children with medium-chain acyl-CoA dehydrogenase deficiency
A phylogenomic approach to bacterial phylogeny: evidence of a core of genes sharing a common history
Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli
Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era
Ecological significance of microdiversity: identical 16S rRNA gene sequences can be found in bacteria with highly divergent genomes and ecophysiologies
Alternative methods for concatenation of core genes indicate a lack of resolution in deep nodes of the prokaryotic phylogeny
Fine root heterogeneity by branch order: exploring the discrepancy in root turnover estimates between minirhizotron and carbon isotopic methods.
Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli
The nematode Pristionchus pacificus as a model system for integrative studies in evolutionary biology
Pan-genomic analysis to redefine species and subspecies based on quantum discontinuous variation: the Klebsiella paradigm
Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
Impact of genomics on the understanding of microbial evolution and classification: the importance of Darwin's views on classification
Horizontal gene transfer: essentiality and evolvability in prokaryotes, and roles in evolutionary transitions
A New Analysis of Archaea-Bacteria Domain Separation: Variable Phylogenetic Distance and the Tempo of Early Evolution.
Tensions and exclusions: the knotty policy encounter between sexual and reproductive health and rights and HIV.
CRISPR Ribonucleases Deactivation
CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on mechanisms that underlie deactivation of CRISPR ribonucleases. Here is the latest research.
Recent advances in genomic sequencing has led to the discovery of new strains of Archaea and shed light on their evolutionary history. Discover the latest research on Archaeogenetics here.