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How the tortoise beats the hare: Slow and steady adaptation in structured populations suggests a rugged fitness landscape in bacteria

bioRxiv

Jun 3, 2014

Joshua R. NahumBenjamin Kerr

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Abstract

In the context of Wright's adaptive landscape, genetic epistasis can yield a multi-peaked or "rugged" topography. In an unstructured population, a lineage with selective access to multiple peaks is expected to rapidly fix on one, which may not be the highest peak. Contrarily, beneficial...read more

Mentioned in this Paper

Turtle
Landscapes
Hares (mammal)
Simulation
Genetic Techniques
Population Group
Adaptation
Patterns
Epistasis, Genetic
Pharmaceutical Preparations
5
9
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  • How the tortoise beats the hare: Slow and steady adaptation in structured populations suggests a rugged fitness landscape in bacteria

    bioRxiv

    Jun 3, 2014

    Joshua R. NahumBenjamin Kerr

    PMID: 990005793

    DOI: 10.1101/005793

    Abstract

    In the context of Wright's adaptive landscape, genetic epistasis can yield a multi-peaked or "rugged" topography. In an unstructured population, a lineage with selective access to multiple peaks is expected to rapidly fix on one, which may not be the highest peak. Contrarily, beneficial...read more

    Mentioned in this Paper

    Turtle
    Landscapes
    Hares (mammal)
    Simulation
    Genetic Techniques
    5
    9

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