PMID: 1748945Jan 1, 1991

How to assess fetal metabolic acidosis from cord samples

Journal of Perinatal Medicine
K G Rosén, K W Murphy

Abstract

The degree of metabolic acidosis at birth has been calculated in cord artery and vein samples from 21 term fetuses with cord artery pH less than 7.20. The aim of the study was to compare base deficit values calculated from either Siggaard-Andersen alignment nomogram (BD blood) or the Acid-Base chart (BD extra cellular fluid, BDecf). BDblood was found to be consistently higher in the cord artery as compared with BDecf, 13.2 +/- 3.5 and 9.9 +/- 2.9 mmol/l (Mean +/- SD), respectively. A significant correlation was found between cord artery PCO2 and BDblood whereas BDecf appeared unaffected by PCO2. In cases with cord entanglement BDecf a-v differences were increased to 3.4 +/- 2.3 mmol/l as compared with the small a-v difference noted in acidotic cases without cord entanglement, 1.1 +/- 1.25 mmol/l. It is speculated that with acutely emerging, intermittent asphyxia due to cord compression, a cord artery and vein difference in metabolic acidosis may exist and where the vein captures the basal level and the artery the acute changes. It is concluded that BDecf in both cord artery and vein add valuable information on the mechanisms behind metabolic acidosis.

References

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Citations

Dec 5, 1998·Obstetrics and Gynecology·K KrügerM Westgren
Oct 13, 1999·Artificial Intelligence in Medicine·J M GaribaldiE C Ifeachor
Sep 1, 1996·Midwifery·M HarrisK R Greene
Jun 9, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·K G RosénH Norén
Dec 8, 2016·Obstetrics and Gynecology·Inês NunesFetal Monitoring and Alert (FM-ALERT) Study Group
Dec 31, 2016·American Journal of Obstetrics and Gynecology·Steven L ClarkThomas J Garite
Dec 10, 1999·Obstetrics and Gynecology Clinics of North America·K R Greene
Nov 1, 1995·American Journal of Obstetrics and Gynecology·M WestgrenL Nordström
Oct 25, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·I Amer-Wahlin, K G Rosén
Mar 11, 2005·Current Opinion in Obstetrics & Gynecology·K G Rosén
Sep 16, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·G A B KroK G Rosén
Dec 1, 1994·British Journal of Obstetrics and Gynaecology·J WestgateK R Greene
Feb 8, 2003·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·I Amer-WahlinK G Rosén
Oct 30, 1998·Obstetrical & Gynecological Survey·L Nordström, S Arulkumaran
Apr 24, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Parisa MokaramiPer Olofsson

Related Concepts

Acidosis, Lactic
Carbon Dioxide
Umbilical Cord Blood
Hydrogen-Ion Concentration
Structure of Umbilical Artery
Umbilical Vein

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