How to assess stress biomarkers for idiographic research?

Psychoneuroendocrinology
Sonja L van OckenburgKarin A M Janssens

Abstract

Associations between stress-related biomarkers, like cortisol or catecholamines, and somatic or psychological symptoms have often been examined at the group level. Studies using this nomothetic approach reported equivocal findings, which may be due to high levels of intra-individual variance of stress biomarkers. More importantly, analyses at the group level provide information about the average patient, but do not necessarily have meaning for individual patients. An alternative approach is to examine data at the level of individual patients in so-called idiographic research. This method allows identifying individuals in whom symptoms are explained by preceding alterations in specific stress biomarkers, based on time series of symptoms and stress biomarkers. To create time series of sufficient length for statistical analysis, many subsequent stress biomarker measurements are needed for each participant. In the current paper, different matrices (i.e. saliva, urine, nail and hair) are discussed in light of their applicability for idiographic research. This innovative approach might lead to promising new insights in the association between stress biomarkers and psychological or somatic symptoms. New collection tools for stress bio...Continue Reading

References

Feb 1, 1991·The British Journal of Dermatology·V A Randall, F J Ebling
Jan 1, 1990·Psychoneuroendocrinology·C KirschbaumD H Hellhammer
Nov 1, 1988·Annals of Clinical Biochemistry·S A BinghamJ H Cummings
May 1, 1970·The British Journal of Dermatology·R Dawber
Jan 1, 1980·Archives of Internal Medicine·W B Bean
Aug 1, 1994·Journal of Affective Disorders·M C GordijnR H Van den Hoofdakker
Oct 1, 1993·American Industrial Hygiene Association Journal·M F BoenigerJ Rosenberg
Nov 5, 1998·Psychoneuroendocrinology·A D Clements, C R Parker
Apr 16, 1999·Psychosomatic Medicine·E L GibsonJ Wardle
Feb 26, 2000·Forensic Science International : Synergy·R Wennig
Jun 6, 2003·Journal of Abnormal Psychology·Frenk PeetersMarten deVries
Nov 8, 2003·Psychoneuroendocrinology·Ilona FederenkoClemens Kirschbaum
Jan 17, 2004·Journal of the American Academy of Dermatology·C Ralph DanielAntonella Tosti
Apr 28, 2005·Psychoneuroendocrinology·Daniel J HruschkaCarol M Worthman
Jun 9, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yu Chen BarrettOle Vesterqvist
Aug 6, 2005·Scandinavian Journal of Clinical and Laboratory Investigation·A H Garde, A M Hansen
Nov 1, 2005·Arthritis and Rheumatism·Samuel A McLeanDaniel J Clauw
May 21, 2008·International Journal of Cosmetic Science·D A R de BerkerR Baran
Jul 9, 2008·Scandinavian Journal of Clinical and Laboratory Investigation·Ase Marie HansenRoger Persson
Aug 30, 2008·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Lynne M AusmanJohanna T Dwyer
Sep 2, 2008·Clinical Chemistry·Michael Gröschl
Oct 11, 2008·Dermatologic Therapy·Valerie Anne Randall
Jan 22, 2009·Psychoneuroendocrinology·Nicolas Rohleder, Urs M Nater
Feb 16, 2010·Clinical Biochemistry·Wei GaoZuhong Lu
May 26, 2010·Climacteric : the Journal of the International Menopause Society·E S Mitchell, N F Woods
Aug 27, 2010·The Journal of Clinical Endocrinology and Metabolism·Nicole VogelzangsBrenda W J H Penninx
Sep 16, 2010·Nature Reviews. Neuroscience·Stafford L Lightman, Becky L Conway-Campbell
Sep 24, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marloes J A G HenckensGuillén Fernández
Nov 3, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Amanda F HamelMelinda A Novak
Feb 16, 2011·Journal of Abnormal Psychology·Lauren M BylsmaJonathan Rottenberg
Mar 9, 2011·Forensic Science International : Synergy·Marc A LeBeauJason D Brewer
Sep 16, 2011·Psychoneuroendocrinology·Tobias StalderClemens Kirschbaum

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Citations

Mar 15, 2019·Journal of Research on Adolescence : the Official Journal of the Society for Research on Adolescence·Elizabeth J SusmanNilam Ram
Feb 16, 2019·Women's Midlife Health·Lynnette Leidy SievertNancy Fugate Woods

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