How to decrease bronchopulmonary dysplasia in your neonatal intensive care unit today and "tomorrow"

F1000Research
Leif D Nelin, Vineet Bhandari

Abstract

Bronchopulmonary dysplasia, or BPD, is the most common chronic lung disease in infants. Genetic predisposition and developmental vulnerability secondary to antenatal and postnatal infections, compounded with exposure to hyperoxia and invasive mechanical ventilation to an immature lung, result in persistent inflammation, culminating in the characteristic pulmonary phenotype of BPD of impaired alveolarization and dysregulated vascularization. In this article, we highlight specific areas in current management, and speculate on therapeutic strategies that are on the horizon, that we believe will make an impact in decreasing the incidence of BPD in your neonatal intensive care units.

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Citations

Dec 14, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·Zuzanna KubickaJohn Fiascone
Feb 22, 2018·Journal of Translational Medicine·Nicola PrincipiSusanna Esposito
Mar 14, 2019·Pediatric Pulmonology·Vineet Bhandari
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Jul 27, 2020·F1000Research·Mitali Sahni, Vineet Bhandari
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Jun 15, 2017·American Journal of Respiratory and Critical Care Medicine·Angelo D'AlessandroKurt R Stenmark
Sep 7, 2018·Pediatric Research·John Ibrahim, Vineet Bhandari
May 21, 2021·Pediatric Research·Richard SindelarUNKNOWN Bronchopulmonary Dysplasia Collaborative
Nov 14, 2020·Jornal de pediatria·Vineet Bhandari, Mitali Sahni
Aug 20, 2021·Pediatric Health, Medicine and Therapeutics·Marissa HennellySamia Aleem

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Methods Mentioned

BETA
PMA

Software Mentioned

Survanta®

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