How to detect and correct myocardial creep in myocardial perfusion imaging using Rubidium-82 PET?

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
S S KoendersJorn A van Dalen

Abstract

Reliability of myocardial blood flow (MBF) quantification in myocardial perfusion imaging (MPI) using PET can majorly be affected by the occurrence of myocardial creep when using pharmacologically induced stress. In this paper, we provide instructions on how to detect and correct for myocardial creep. For example, in each time frame of the PET images the myocardium contour and the observed activity have to be compared to check for misalignments. In addition, we provide an overview of the functionality of commonly used software packages to perform this quality control step as not all software packages currently provide this functionality. Furthermore, important clinical considerations to obtain accurate MBF measurements are given.

References

Aug 6, 2004·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R ParkashR S B Beanlands
Jun 19, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Cesar A SantanaFabio P Esteves
Mar 15, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Maria C ZiadiRob S B Beanlands
Apr 15, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jonathan B MoodyVenkatesh L Murthy
May 17, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Benjamin C LeeVenkatesh L Murthy
Jul 9, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ran KleinRobert A deKemp
Dec 16, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Venkatesh L MurthyJames R Corbett
Feb 23, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·S S KoendersJ A van Dalen

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Citations

Sep 18, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·S S KoendersJ D van Dijk
Sep 22, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Martin Lyngby Lassen, Piotr J Slomka
Mar 4, 2021·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·S S KoendersJ A van Dalen
Nov 27, 2021·Physics in Medicine and Biology·Iraj MohammadiJoão Veloso

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Software Mentioned

SyngoMBF
FlowQuant
Corridor4DM
Invia

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