How to Obtain a Reliable Estimate of Occupational Exposure? Review and Discussion of Models' Reliability

International Journal of Environmental Research and Public Health
Andrea SpinazzèDomenico Maria Cavallo

Abstract

Evaluation and validation studies of quantitative exposure models for occupational exposure assessment are still scarce and generally only consider a limited number of exposure scenarios. The aim of this review was to report the current state of knowledge of models' reliability in terms of precision, accuracy, and robustness. A systematic review was performed through searches of major scientific databases (Web of Science, Scopus, and PubMed), concerning reliability of Tier1 ("ECETOC TRA"-European Centre for Ecotoxicology and Toxicology of Chemicals Targeted Risk Assessment, MEASE, and EMKG-Expo-Tool) and Tier2 models (STOFFENMANAGER® and "ART"-Advanced Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) Tool). Forty-five studies were identified, and we report the complete information concerning model performance in different exposure scenarios, as well as between-user reliability. Different studies describe the ECETOC TRA model as insufficient conservative to be a Tier1 model, in different exposure scenarios. Contrariwise, MEASE and EMKG-Expo-Tool seem to be conservative enough, even if these models have not been deeply evaluated. STOFFENMANAGER® resulted the most balanced and robust model. Finally, ART...Continue Reading

References

Aug 27, 1999·Applied Occupational and Environmental Hygiene·J W Cherrie
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Sep 24, 2009·Occupational and Environmental Medicine·Jody SchinkelErik Tielemans
Mar 16, 2011·Journal of Environmental Monitoring : JEM·Jody SchinkelErik Tielemans
May 4, 2011·International Journal of Occupational Medicine and Environmental Health·Małgorzata Kupczewska-DobeckaMarek Jakubowski
May 6, 2011·Journal of Environmental Monitoring : JEM·Patricia E Mc DonnellErik L Tielemans
Jul 20, 2012·Environmental Toxicology and Pharmacology·Małgorzata Kupczewska-DobeckaSławomir Brzeźnicki
Jan 31, 2013·Journal of Exposure Science & Environmental Epidemiology·Rosemary T ZaleskiChris Money
Jan 24, 2015·Risk Analysis : an Official Publication of the Society for Risk Analysis·R A RiedmannD Vernez
Apr 11, 2015·The Annals of Occupational Hygiene·Hanna E LandbergHåkan Tinnerberg
Dec 24, 2015·International Journal of Occupational Safety and Ergonomics : JOSE·Agnieszka JankowskaMałgorzata Kupczewska-Dobecka
Jul 1, 2016·The Annals of Occupational Hygiene·Nenad SavicDavid Vernez
Mar 30, 2017·Annals of Work Exposures and Health·Andrea SpinazzèDomenico M Cavallo
Mar 30, 2017·Annals of Work Exposures and Health·Hanna E LandbergHåkan Tinnerberg
Apr 6, 2017·Annals of Work Exposures and Health·G A Henri Heussen, Albert L Hollander
Oct 14, 2017·Annals of Work Exposures and Health·Martie van TongerenSusanne Hesse
Oct 14, 2017·Annals of Work Exposures and Health·Wouter Fransman
Oct 14, 2017·Annals of Work Exposures and Health·Martin TischerMartie van Tongeren
Oct 14, 2017·Annals of Work Exposures and Health·Judith LambMartie Van Tongeren
Dec 22, 2017·Annals of Work Exposures and Health·Nenad SavicDavid Vernez
Mar 2, 2018·Journal of Occupational and Environmental Hygiene·Antti J KoivistoIsmo K Koponen
Jun 4, 2018·International Journal of Hygiene and Environmental Health·Jihoon ParkKiyoung Lee
Oct 12, 2018·International Journal of Environmental Research and Public Health·Aduldatch SailabahtJohn Cherrie
Oct 30, 2018·Annals of Work Exposures and Health·Hanna E LandbergHåkan Tinnerberg
Nov 1, 2018·Annals of Work Exposures and Health·Volker MostertMatthias Wormuth
Nov 18, 2018·Annals of Work Exposures and Health·Seokwon LeeHyunwook Kim
Dec 12, 2018·Annals of Work Exposures and Health·Eun Gyung LeeMartin Harper
Dec 12, 2018·Annals of Work Exposures and Health·Eun Gyung LeeMartin Harper
Mar 10, 2019·Annals of Work Exposures and Health·Henk A GoedeJody Schinkel
Apr 2, 2019·The Science of the Total Environment·C RibaltaM Viana
May 24, 2019·Annals of Work Exposures and Health·Nenad SavicDavid Vernez

❮ Previous
Next ❯

Citations

Jan 16, 2020·International Journal of Environmental Research and Public Health·John William CherrieKeld Alstrup Jensen
Jul 2, 2020·International Journal of Environmental Research and Public Health·Urs Schlueter, Martin Tischer
Jun 18, 2020·International Journal of Environmental Research and Public Health·Andrea SpinazzèDomenico Maria Cavallo
Nov 19, 2020·International Journal of Environmental Research and Public Health·Jan UrbanusMatthias Wormuth
Aug 8, 2021·International Journal of Environmental Research and Public Health·Stefan HahnUrs Schlüter
Aug 9, 2021·Annals of Work Exposures and Health·Antti Joonas KoivistoSusan Arnold

❮ Previous
Next ❯

Software Mentioned

MEASE
ECETOC TRAv3
STOFFENMANAGER
MEGA
ECETOC
- Expo
EASE
EMKG Expo - Tool REACH Tool
Tool
PubMed

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Work Exposures and Health
Andrea SpinazzèDomenico Maria Cavallo
Annals of Work Exposures and Health
Hanna E LandbergHåkan Tinnerberg
Journal of Exposure Science & Environmental Epidemiology
R ZaleskiChris D Money
© 2021 Meta ULC. All rights reserved