How user knowledge of psychotropic drug withdrawal resulted in the development of person-specific tapering medication

Therapeutic Advances in Psychopharmacology
Peter C Groot, Jim van Os

Abstract

Coming off psychotropic drugs can cause physical as well as mental withdrawal, resulting in failed withdrawal attempts and unnecessary long-term drug use. The first reports about withdrawal appeared in the 1950s, but although patients have been complaining about psychotropic withdrawal problems for decades, the first tentative acknowledgement by psychiatry only came in 1997 with the introduction of the 'antidepressant-discontinuation syndrome'. It was not until 2019 that the UK Royal College of Psychiatrists, for the first time, acknowledged that withdrawal can be severe and persistent. Given the lack of a systematic professional response, over the years, patients who were experiencing withdrawal started to work out practical ways to safely come off medications themselves. This resulted in an experience-based knowledge base about withdrawal which ultimately, in The Netherlands, gave rise to the development of person-specific tapering medication (so-called tapering strips). Tapering medication enables doctors, for the first time, to flexibly prescribe and adapt the medication required for responsible and person-specific tapering, based on shared decision making and in full agreement with recommendations in existing guidelines. L...Continue Reading

References

Apr 1, 1997·The Journal of Clinical Psychiatry·M LejoyeuxJ Adès
Jul 1, 1997·The Journal of Clinical Psychiatry·J ZajeckaS Mitchell
Apr 29, 1998·BMJ : British Medical Journal·P HaddadA Young
Feb 20, 1961·Psychopharmacologia·L E HOLLISTERR O DEGAN
Dec 1, 1961·The American Journal of Psychiatry·J C KRAMERM FINK
Aug 24, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Giovanni A Fava, Emanuela Offidani
May 7, 2011·Expert Opinion on Drug Safety·Istvan BitterPal Czobor
Feb 28, 2015·Psychotherapy and Psychosomatics·Guy Chouinard, Virginie-Anne Chouinard
Feb 28, 2015·Psychotherapy and Psychosomatics·Giovanni A FavaEmanuela Offidani
Jan 29, 2016·Psychotherapy and Psychosomatics·Marieke WichersUNKNOWN Psychosystems, ESM Group, EWS Group
Feb 3, 2016·Therapeutic Advances in Psychopharmacology·Emma Wilson, Malcolm Lader
Aug 17, 2016·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Renske C BosmanNeeltje M Batelaan
Nov 3, 2016·The New England Journal of Medicine·Arabella L Simpkin, Richard M Schwartzstein
Jun 20, 2018·Proceedings of the National Academy of Sciences of the United States of America·Aaron J FisherBertus F Jeronimus
Jul 18, 2018·Psychotherapy and Psychosomatics·Giovanni A FavaJenny Guidi
Aug 28, 2018·Psychotherapy and Psychosomatics·Giovanni A Fava, Carlotta Belaise
Mar 10, 2019·The Lancet. Psychiatry·Mark Abie Horowitz, David Taylor
Apr 4, 2019·The Behavioral and Brain Sciences·John P A Ioannidis
Apr 25, 2019·The New England Journal of Medicine·Deborah DowellRoger Chou
May 22, 2019·BMJ : British Medical Journal·James DaviesAnne Guy
Jun 25, 2019·The Lancet. Psychiatry·Henricus G RuheUNKNOWN Discontinuation of Antidepressants Taskforce
Oct 4, 2019·BMJ : British Medical Journal·David Healy, Dee Mangin
Nov 28, 2019·The Journal of Clinical Psychiatry·Giovanni A Fava, Fiammetta Cosci
Jan 9, 2020·The Lancet. Public Health·Peter C Groot, Jim van Os

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Citations

Sep 22, 2020·Therapeutic Advances in Psychopharmacology·Peter C Groot, Jim van Os
Nov 24, 2020·Therapeutic Advances in Psychopharmacology·David Cohen, Alexander Recalt
Apr 3, 2021·Therapeutic Advances in Psychopharmacology·Miriam Larsen-Barr, Fred Seymour
Sep 3, 2021·Therapeutic Advances in Psychopharmacology·Peter C Groot, Jim van Os

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Methods Mentioned

BETA
pharmacotherapy

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