How we do it: surgery should be considered equally with I131 and thionamide treatment as first-line therapy for thyrotoxicosis

Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
R J A EnglandS L Atkin

Abstract

Radioiodine and thionamide treatment are the most frequently used treatment modalities for thyrotoxicosis in Europe and North America with surgery being reserved for selected cases. * In our clinic patients were offered all three modalities via simultaneous interview with an endocrinologist and a surgeon, with international risk benefit data for radioiodine and thionamide therapy, and local risk benefit data for total thyroidectomy provided. * When given the choice, at least 15% of patients opted for total thyroidectomy over the other modalities. * In our series of 100 consecutive surgical patients there was a 4% malignancy rate. * Total thyroidectomy should be offered equally, with radioiodine and thionamide treatment, as a first line treatment modality in the management of thyrotoxicosis.

References

Jun 16, 1994·The New England Journal of Medicine·J A Franklyn
Mar 6, 2003·Clinical Medicine : Journal of the Royal College of Physicians of London·Jayne Franklyn
Mar 12, 2003·The Journal of Clinical Endocrinology and Metabolism·William D LeslieElizabeth A Cowden

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Citations

Apr 7, 2007·BMJ : British Medical Journal·R James A England, Steve Atkin
Apr 2, 2011·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Mala SharmaHarit Desai

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