How well are patients doing up to 30 years after a mustard operation?

The Thoracic and Cardiovascular Surgeon
Jürgen HörerRüdiger Lange

Abstract

Right heart failure and baffle complications may affect the health status of patients with transposition of the great arteries after an atrial switch operation. This study aims to identify risk factors for late death, the incidence of reoperations, and the functional status of 88 patients who underwent a Mustard operation with a mean follow-up of 20.9 +/- 10.0 years. There were 7 early and 19 late deaths. Follow-up was complete for 97 % of the hospital survivors. Survival and freedom from reoperation of the hospital survivors at 20 years was 83.7 +/- 4.2 %, and 70.6 +/- 5.4 %, respectively. Seven reoperations were performed for systemic ventricular failure, and 24 for baffle complications, with no operative mortality. Presence of a ventricular septal defect at the time of the Mustard operation was predictive for late death in multivariate analysis ( P = 0.040). At follow-up, 82 % of the patients were able to work full-time, 11 % part-time, and 7 % experienced noticeable limitations of their activities. Presence of a VSD at the time of the Mustard operation defines a distinct subgroup with an increased risk for late death. Long-term survivors were in a good functional status but had to be reoperated frequently due to baffle comp...Continue Reading

Citations

Mar 20, 2014·European Heart Journal·Judith A A E CuypersJ W Roos-Hesselink
Dec 27, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Andreas P KalogeropoulosWendy M Book
Jul 14, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David L JoyceLyle D Joyce
Jun 2, 2009·International Journal of Cardiology·Giovanni Di SalvoRaffaele Calabrò
Oct 27, 2009·The Annals of Thoracic Surgery·Basar SareyyupogluHartzell V Schaff
Jan 15, 2014·International Journal of Cardiology·Timothy CottsAlliance for Adult Research in Congenital Cardiology (AARCC)
Oct 4, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Maulin U VoraNicholas W Markin
Jul 11, 2017·Cardiology in the Young·Alexandra SoufiAdrienne H Kovacs
Nov 12, 2018·Heart·Lotte E CouperusRoderick W C Scherptong

Related Concepts

2D Echocardiography
Health Status
Postoperative Period
Repeat Surgery
Retrospective Studies
Cardiovascular Surgical Procedures
Transposition of Great Vessels

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