Hox cluster organization in the jawless vertebrate Petromyzon marinus

The Journal of Experimental Zoology
A ForceJohn H Postlethwait

Abstract

Large-scale gene amplifications may have facilitated the evolution of morphological innovations that accompanied the origin of vertebrates. This hypothesis predicts that the genomes of extant jawless fish, scions of deeply branching vertebrate lineages, should bear a record of these events. Previous work suggests that nonvertebrate chordates have a single Hox cluster, but that gnathostome vertebrates have four or more Hox clusters. Did the duplication events that produced multiple vertebrate Hox clusters occur before or after the divergence of agnathan and gnathostome lineages? Can investigation of lamprey Hox clusters illuminate the origins of the four gnathostome Hox clusters? To approach these questions, we cloned and sequenced 13 Hox cluster genes from cDNA and genomic libraries in the lamprey, Petromyzon marinus. The results suggest that the lamprey has at least four Hox clusters and support the model that gnathostome Hox clusters arose by a two-round-no-cluster-loss mechanism, with tree topology [(AB)(CD)]. A three-round model, however, is not rigorously excluded by the data and, for this model, the tree topologies [(D(C(AB))] and [(C(D(AB))] are most parsimonious. Gene phylogenies suggest that at least one Hox cluster du...Continue Reading

References

Jan 24, 1992·Cell·W McGinnis, R Krumlauf
Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·K SchughartF H Ruddle
Mar 1, 1983·The Quarterly Review of Biology·R G Northcutt, C Gans
Dec 1, 1993·Current Opinion in Genetics & Development·C Kappen, F H Ruddle
Jul 29, 1994·Cell·R Krumlauf
Aug 18, 1994·Nature·J Garcia-Fernández, P W Holland
Jul 1, 1994·Genetics·W McGinnis
Jul 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·J W PendletonF H Ruddle
Sep 1, 1993·Developmental Biology·J S Eisen, J A Weston
Feb 1, 1996·Developmental Biology·P W Holland, J Garcia-Fernàndez
Jan 1, 1996·Genetics·J Zhang, M Nei
Feb 15, 1996·The Journal of Experimental Zoology·B Y MisofG P Wagner
Nov 1, 1996·Genetics·A MochizukiY Iwasa
Dec 1, 1996·Current Opinion in Genetics & Development·A Sidow
Mar 14, 1997·Science·S Dickman
Aug 1, 1997·Molecular Biology and Evolution·W J BaileyF H Ruddle
Jan 23, 1998·The Journal of Experimental Zoology·J L CarrF H Ruddle
Apr 18, 1998·Proceedings of the National Academy of Sciences of the United States of America·M Kmita-CunisseW J Gehring
May 26, 1998·Annals of the New York Academy of Sciences·J Piatigorsky
Jun 20, 1998·Development Genes and Evolution·T UekiS Aizawa
Nov 30, 1998·Science·A AmoresJ H Postlethwait
Feb 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·P MartinezE H Davidson
Jul 23, 1999·Annals of the New York Academy of Sciences·F H RuddleG P Wagner
Aug 12, 1999·Journal of Molecular Evolution·A Stoltzfus
Aug 24, 1999·Developmental Biology·H WadaP W Holland
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·A Abzhanov, T C Kaufman
Dec 14, 1999·Journal of Molecular Evolution·S KurakuT Miyata
Mar 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·C B KimF Ruddle
Mar 18, 2000·Developmental Biology·W R JackmanC B Kimmel
Apr 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·D GauchatB Galliot
May 18, 2000·Biochemical Society Transactions·T J Gibson, J Spring
Aug 11, 2000·Evolution; International Journal of Organic Evolution·A E Faivre
Sep 21, 2000·Current Biology : CB·S L Pollard, P W Holland
Oct 3, 2000·Nature·M F Heyworth

❮ Previous
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Citations

Jun 29, 2005·Journal of Molecular Evolution·Marc Robinson-RechaviAnn Sluder
Jan 19, 2008·Theory in Biosciences = Theorie in Den Biowissenschaften·Sonja J Prohaska, Peter F Stadler
Apr 6, 2004·Molecular Phylogenetics and Evolution·Sonja J ProhaskaPeter F Stadler
Dec 10, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Pedro Martinez, Chris T Amemiya
May 25, 2004·Nature·Yoko TakioShigeru Kuratani
Feb 24, 2006·Proceedings of the National Academy of Sciences of the United States of America·Guangjun ZhangMartin J Cohn
May 2, 2008·Proceedings of the National Academy of Sciences of the United States of America·Shigehiro KurakuShigeru Kuratani
Oct 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Susanne DreborgDan Larhammar
Sep 18, 2013·Proceedings of the National Academy of Sciences of the United States of America·Tarang K MehtaByrappa Venkatesh
Feb 6, 2008·Zebrafish·Evdokia DodouJohn H Postlethwait
Jan 7, 2004·Genome Research·Angel AmoresJohn H Postlethwait
Jul 4, 2013·BMC Developmental Biology·Juan Pascual-AnayaJordi Garcia-Fernàndez
Mar 10, 2009·Zoological Science·Rebecca F Furlong, John F Mulley
Mar 10, 2009·Zoological Science·Shigehiro Kuraku
Feb 4, 2014·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Ingo BraaschJohn H Postlethwait
Apr 24, 2014·Neural Development·Alejandro Pinzón-OlejuaClaudia Ao Stuermer
Jan 28, 2003·Proceedings of the National Academy of Sciences of the United States of America·Esther G L KohByrappa Venkatesh
Nov 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Gunte P WagnerFrank Ruddle
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Vydianathan RaviByrappa Venkatesh
Jul 11, 2014·General and Comparative Endocrinology·Ingo Braasch, Manfred Schartl
Oct 3, 2002·Evolution & Development·William R Jackman, Charles B Kimmel
Oct 10, 2008·Molecular Biology and Evolution·Shigehiro KurakuShigeru Kuratani
Aug 1, 2008·Journal of Fish Biology·S M Zou, X Y Jiang
Dec 1, 2004·Annual Review of Genetics·John S Taylor, Jeroen Raes
Mar 19, 2004·Current Biology : CB·David E K Ferrier
Oct 4, 2005·Molecular Phylogenetics and Evolution·An MannaertLuc Leyns
Dec 25, 2003·Molecular Biology and Evolution·Marc Robinson-RechaviVincent Laudet
Apr 1, 2004·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Claudia FriedPeter F Stadler
Sep 26, 2003·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Claudia FriedPeter F Stadler
Oct 16, 2013·The Journal of Comparative Neurology·Juan Pérez-FernándezManuel A Pombal
Oct 28, 2006·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·John H Postlethwait
Apr 22, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Tetsuro Ikuta, Hidetoshi Saiga
May 22, 2009·Annals of the New York Academy of Sciences·Dan LarhammarTomas A Larsson
Oct 1, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
Aug 12, 2010·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Jian YuanShuming Zou
Jan 8, 2011·Evolution & Development·Eva Jimenez-Guri, Cristina Pujades
Dec 21, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Mark E DeVriesDavid J Kelvin

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