Hox genes and chordate evolution

Developmental Biology
P W Holland, Jordi Garcia-Fernàndez

Abstract

Hox genes are implicated in the control of axial patterning during embryonic development of many, perhaps all, animals. Here we review recent data on Hox gene diversity, genomic organization, and embryonic expression in chordates (including tunicates, amphioxus, hagfish, lampreys, teleosts) plus their putative sister group, the hemichordates. We consider the potential of comparative Hox gene data to resolve some outstanding controversies in chordate phylogeny. The use of Hox gene expression patterns to identify homologies between body plans both within the vertebrates and between the chordate subphyla is also discussed. Homology between the vertebrate hindbrain and an extensive region of amphioxus neural tube is suggested by comparison of Hox-3 homologues and strengthened by new data on amphioxus Hox-1 gene expression reported here. Finally, we give two examples of how Hox genes are giving glimpses into chordate developmental evolution. The first relates changes in Hox gene expression to transposition of vertebral of vertebral identities; the second describes a correlation between vertebrate origins and Hox gene cluster duplication. We suggest that the simultaneous duplication of many classes of genes, often interacting in gene...Continue Reading

Citations

Oct 21, 1998·The Journal of Comparative Neurology·S Candiani, M Pestarino
Aug 11, 1999·The Journal of Comparative Neurology·L ManniP Burighel
Jan 1, 1996·Developmental Genetics·E M Eddy
Mar 29, 2001·American Journal of Physical Anthropology·D S Strait
Dec 18, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·C Redies, L Puelles
Sep 23, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·E DahlR Balling
Jan 12, 2005·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Andrea TanzerPeter F Stadler
Jun 7, 2008·Journal of Molecular Evolution·Han Wang
Oct 3, 2006·Development Genes and Evolution·Yuko HaraShonan Amemiya
Apr 12, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Yushuang LinHongwei Zhang
May 12, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Yongjun WangLei Wang
Mar 19, 2013·Progress in Biophysics and Molecular Biology·David A Lovejoy, Dalia Barsyte-Lovejoy
Jan 19, 2008·Theory in Biosciences = Theorie in Den Biowissenschaften·Sonja J Prohaska, Peter F Stadler
Nov 27, 1999·Mechanisms of Ageing and Development·E Richelle-Maurer, G Van de Vyver
Nov 14, 2000·Trends in Neurosciences·L W Swanson
Feb 1, 2000·Trends in Genetics : TIG·S Aparicio
Feb 11, 1999·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·M E Hahn
Nov 8, 2001·Current Opinion in Cell Biology·P A Trainor, R Krumlauf
Dec 10, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Pedro Martinez, Chris T Amemiya
Jan 15, 2005·Nature·Arne KusserowThomas W Holstein
Apr 16, 1998·Nature Genetics·J H PostlethwaitW S Talbot
Feb 9, 2010·Proceedings of the National Academy of Sciences of the United States of America·Chris T AmemiyaPeter F Stadler
Sep 18, 2013·Proceedings of the National Academy of Sciences of the United States of America·Tarang K MehtaByrappa Venkatesh
Oct 1, 1996·Proceedings of the National Academy of Sciences of the United States of America·D W StockK M Weiss
Jul 14, 2011·Stem Cells and Development·Marilaine FournierJanet J Bijl
Aug 5, 2005·Molecular Biology and Evolution·Jongmin Nam, Masatoshi Nei
Feb 10, 2000·Molecular Biology and Evolution·M D GanforninaD Sánchez
Oct 18, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·H Reichert, A Simeone
Feb 21, 1998·Genes & Development·A R Godwin, M R Capecchi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Biology : CB
Thomas P Powers, Chris T Amemiya
Proceedings of the National Academy of Sciences of the United States of America
Chi-hua ChiuGünter P Wagner
© 2021 Meta ULC. All rights reserved