Huangqi Jianzhong Tang for Treatment of Chronic Gastritis: A Systematic Review of Randomized Clinical Trials

Evidence-based Complementary and Alternative Medicine : ECAM
Yue WeiJin-Xiang Yang

Abstract

To assess the clinical effects and safety of Huangqi Jianzhong Tang (HQJZ) for the treatment of chronic gastritis (CG), three English databases and four Chinese databases were searched through the inception to January 2015. In randomized controlled trials (RCTs) comparing HQJZ with placebo, no intervention and western medicine were included. A total of 9 RCTs involving 979 participants were identified. The methodological quality of the included trials was generally poor. Meta-analyses demonstrated that HQJZ plus conventional medicine was more effective in improving overall gastroscopy outcome than western medicine alone for treatment of chronic superficial gastritis with the pooling result of overall improvement [OR 3.78 (1.29,11.06), P = 0.02]. In addition, the combination of HQJZ with antibiotics has higher overall effect rate than antibiotics alone for the treatment of CG [OR 2.60 (1.49,4.54), P = 0.0007]. There were no serious adverse events reported in both the intervention and controlled groups. HQJZ has the potential of improvement of the patients' gastroscopy outcomes, Helicobacter pylori clearance rate, traditional Chinese Medicine syndromes, and overall effect rate alone or in combination use with conventional western...Continue Reading

References

Nov 26, 2003·The American Journal of Gastroenterology·Yelda Leal-HerreraOnofre Muñoz
Mar 3, 2005·Journal of Gastroenterology and Hepatology·Nasrin ZendehdelFarideh Siavoshi
Dec 5, 2006·Gut·Massimo RuggeDavid Y Graham
Apr 12, 2012·Gut·Peter MalfertheinerUNKNOWN European Helicobacter Study Group
Jul 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Duan-Yong LiuJing-Yan Han
Dec 3, 2014·Best Practice & Research. Clinical Gastroenterology·Mariya VarbanovaPeter Malfertheiner

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Citations

Mar 28, 2018·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Ming DongYing Wei
Nov 30, 2019·Biomedical Chromatography : BMC·Yuetao LiuXuemei Qin
Mar 31, 2018·World Journal of Gastroenterology : WJG·Guo-Tao YangAi-Qin Dong
Oct 30, 2020·Biomedical Chromatography : BMC·Dong ZhangYueTao Liu
Nov 5, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Ya-Ru BaoGuo-Xing Zhang
Jul 11, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Ya-Long FengPei Liu
Oct 10, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shan-Qiang Zhang, Ji-Cheng Li

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