PMID: 9451581Feb 6, 1998Paper

Human and monkey P3-like responses in a mixed modality paradigm: effects of context and context-dependent noradrenergic influences

International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology
J A PinedaJ Kubrin

Abstract

Previous studies in non-human primates have reported that noradrenergic agents, such as the alpha 2 agonist clonidine, affect auditory but not visual P3 responses. One explanation for these effects may be that distinct modalities are differentially susceptible to noradrenergic influences--a modality-dependent effect. Another possibility is that noradrenergic effects are modality-independent but context-dependent. Two separate experiments, in humans and monkeys, examined the role of stimulus modality, context and noradrenergic activity in an attempt to elucidate the nature of the relationship between P3 and the action of this catecholamine neurotransmitter. In Experiment 1, human subjects were exposed to two versions of a mixed modality oddball paradigm. In one version, the context or background activity was auditory, while in the other it was visual. In both versions of the paradigm, the same auditory and visual rare targets occurred. The results indicated that N2 and P3 to visual targets were more sensitive to changes in context than those to auditory targets. In both cases, N2 and P3 amplitudes to targets were enhanced when the eliciting event and context differed. A modality-specific N2b, on the other hand, was enhanced when...Continue Reading

References

May 1, 1977·Journal of Experimental Psychology. Human Perception and Performance·N K SquiresS Grossberg
Oct 1, 1992·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·T W Picton
Mar 1, 1992·Brain Research Bulletin·J A Pineda, D Swick
May 1, 1992·Biological Psychology·E CallawayH Naylor
Sep 1, 1990·Electroencephalography and Clinical Neurophysiology·M E SmithP Chauvel
Oct 1, 1991·Electroencephalography and Clinical Neurophysiology·R L RogersH M Eisenberg
Jan 1, 1991·Progress in Neuro-psychopharmacology & Biological Psychiatry·E CallawayD Brandeis
Dec 1, 1990·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J Polich
Apr 1, 1987·Electroencephalography and Clinical Neurophysiology·G BarrettH Shibasaki
Jan 1, 1988·Electroencephalography and Clinical Neurophysiology·J B HarrisonL L Butcher
Aug 1, 1988·Electroencephalography and Clinical Neurophysiology·J A PinedaT C Holmes
Nov 1, 1989·The International Journal of Neuroscience·I KissP Lordeon
Jun 1, 1989·Psychiatry Research·K C Joseph, N Sitaram
Jan 1, 1989·Psychopharmacology·R HallidayR Lannon
Nov 13, 1989·Brain Research·R T KnightC C Clayworth
Aug 1, 1987·Naunyn-Schmiedeberg's Archives of Pharmacology·D J PettiboneS D Young
Oct 1, 1988·Behavioral Neuroscience·K A PallerS A Hillyard
Apr 1, 1986·Biological Psychology·N E Loveless
Nov 26, 1965·Science·S SuttonE R John
Apr 1, 1983·Electroencephalography and Clinical Neurophysiology·Y C OkadaS J Williamson
Feb 1, 1984·Electroencephalography and Clinical Neurophysiology·C D Yingling, Y Hosobuchi
Sep 1, 1994·Brain Research. Cognitive Brain Research·R VerlegerD Kömpf
Jan 1, 1993·Brain Research Bulletin·J A Pineda, M Westerfield
Feb 1, 1994·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·E CallawayK Herzig
Oct 1, 1995·Biological Psychology·J Polich, A Kok
Jul 21, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·George V Rebec

❮ Previous
Next ❯

Citations

Oct 1, 1999·Environmental Health and Preventive Medicine·J B PanK Morimoto
Aug 3, 2005·Psychological Bulletin·Sander NieuwenhuisJonathan D Cohen
May 1, 2015·The European Journal of Neuroscience·Deirdre M TwomeyRedmond G O'Connell
Feb 12, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T GötzJ Haueisen
Jun 10, 2005·Neuron·Angela J Yu, Peter Dayan
Oct 25, 2017·Neural Computation·Mohammadjavad FarajiWulfram Gerstner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.