Human B-blast specific target determinants in CML: a family study

Tissue Antigens
H E JohnsenF Kissmeyer-Nielsen

Abstract

Human B blast specific target determinants, selectively identified on PWM stimulated purified B lymphoblasts by in vitro generated CTLs, have previously been studied in the population and showed association to and inclusion of HLA-DR geneproducts. This report indicates that B blast target determinants are products of genes which in a codominant mendelain way segregate with the HLA haplotypes in 4 selected families. Furthermore tests of families with HLA-B/D, DR and HLA-D, DR/GLO recombinations show that human B blast specific target determinants are coded from loci (locus) in the HLA-D region, between HLA-B and GLO.

References

Jun 5, 1978·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·W F BodmerJ G Bodmer
May 1, 1976·Tissue Antigens·N GrunnetF Kissmeyer-Nielsen
Nov 1, 1976·Tissue Antigens·T KristensenF Kissmeyer-Nielsen
Dec 1, 1978·The Journal of Experimental Medicine·R TosiD Pressman
May 1, 1979·Transplantation·D AlbrechtsenE Thorsby
Mar 1, 1978·Tissue Antigens·B Bonné-TamirR Zamir
Sep 1, 1981·Acta Physiologica Scandinavica·P Kristensen
Jul 1, 1981·Tissue Antigens·T KristensenC Mawas

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Citations

Aug 1, 1982·Human Immunology·H E JohnsenP W Hansen

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