PMID: 6539863Jul 1, 1984Paper

Human ballistic arm abduction movements: effects of L-dopa treatment in Parkinson's disease

Neurology
A BaroniF Urbani

Abstract

In patients with Parkinson's disease who had never previously been treated with any antiparkinsonism drug, we studied the effects of L-dopa on ballistic arm abduction movement in a step-tracking task. L-Dopa treatment increased the mean velocity of the initial movement towards the target without loss of accuracy and with improved motor performance under open-loop conditions. Performance also improved in motor tasks with expected perturbation. EMG patterns of arm abduction movements showed abnormal features in untreated patients and improved after L-dopa treatment.

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