PMID: 8971013Dec 1, 1996Paper

Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S

Journal of Virology
M Lu, T Shenk

Abstract

Human cytomegalovirus inhibits the growth of human foreskin fibroblast cells by 12 h after infection. Analysis of the cellular DNA content of infected cells by flow cytometry demonstrated that cytomegalovirus does not arrest cell cycle progression at a single point. At least two blockages occur, one of which is in the G1 phase of the cell cycle. The G1 arrest introduced by cytomegalovirus infection blocks S-phase entry after serum stimulation.

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Citations

Nov 25, 1998·Proceedings of the National Academy of Sciences of the United States of America·H ZhuT Shenk
May 4, 1999·FEBS Letters·S B Hwang, K J Park
Feb 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·Yoon-Jae Song, Mark F Stinski
Nov 5, 2002·Journal of Virology·Emanuela NorisSanto Landolfo
Jan 14, 2003·EMBO Reports·Lüder WiebuschChristian Hagemeier
Mar 30, 2011·Cell Research·Sung-Bau LeeLi-Jung Juan
Aug 15, 1998·The Journal of Biological Chemistry·W A BresnahanE A Thompson
Jan 14, 2004·The Journal of General Virology·Lüder WiebuschChristian Hagemeier
Sep 27, 2000·Laboratory Investigation; a Journal of Technical Methods and Pathology·I KosugiY Tsutsui
Dec 13, 2006·Journal of Neuroscience Research·Jenny OdebergCecilia Söderberg-Nauclér
Aug 7, 2007·Reviews in Medical Virology·Mark Bain, John Sinclair
Jan 13, 2009·Clinical Microbiology Reviews·Maxim C-J CheeranMark R Schleiss
Feb 7, 2014·Journal of Virology·Patrick PaladinoLori Frappier
Jan 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·E A FortunatoD H Spector
Aug 10, 2000·Journal of Virology·J P CastilloT F Kowalik
Dec 24, 2003·International Reviews of Immunology·Jonathan P Castillo, Timothy F Kowalik
Feb 22, 2001·The Journal of Experimental Medicine·R M PrestiH W Virgin
Nov 8, 2005·Journal of Neuroscience Research·Maxim C-J CheeranJames R Lokensgard
Mar 8, 2000·Proceedings of the National Academy of Sciences of the United States of America·M L HayashiT Shenk
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·Y ShenT Shenk
Feb 3, 2005·Proceedings of the National Academy of Sciences of the United States of America·Maria C SilvaThomas Shenk
Jan 5, 2011·Protein & Cell·Chonghua Li, Jianping Jin
Jan 8, 2003·Reviews in Medical Virology·Elizabeth A Fortunato, Deborah H Spector
May 4, 2012·The Journal of General Virology·Rachel B GillMark N Prichard

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