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Human demographic history has amplified the effects of background selection across the genome

PLoS Genetics

Jun 19, 2018

Raul TorresRyan D Hernandez

Abstract

Natural populations often grow, shrink, and migrate over time. Such demographic processes can affect genome-wide levels of genetic diversity. Additionally, genetic variation in functional regions of the genome can be altered by natural selection, which drives adaptive mutations to highe...read more

Mentioned in this Paper

Genetic Drift
Abnormal Degeneration
Exons
Genome
Chromosome Map
Sex Chromosomes
Genetics, Population
Recombination, Genetic
Contraction (Finding)
Deleterious Mutation
41
76
2
Paper Details
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Human demographic history has amplified the effects of background selection across the genome

PLoS Genetics

Jun 19, 2018

Raul TorresRyan D Hernandez

PMID: 29912945

DOI: 10.1371/journal.pgen.1007387

Abstract

Natural populations often grow, shrink, and migrate over time. Such demographic processes can affect genome-wide levels of genetic diversity. Additionally, genetic variation in functional regions of the genome can be altered by natural selection, which drives adaptive mutations to highe...read more

Mentioned in this Paper

Genetic Drift
Abnormal Degeneration
Exons
Genome
Chromosome Map
Sex Chromosomes
Genetics, Population
Recombination, Genetic
Contraction (Finding)
Deleterious Mutation
41
76
2

Feeds With Similar Papers

Open Access Genomics Journals

Discover the latest genomics research in this collection of the top open access genomics journals.

Related Papers

Paper Details
References
  • References99
  • Citations7
12345...
  • References99
  • Citations7
1

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